Introduction：Basic information about 4-Chlorophenoxyacetic acid CAS 122-88-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chlorophenoxyacetic acid Basic information
| Product Name: | 4-Chlorophenoxyacetic acid |
| Synonyms: | 2-(4-Chloro-phenoxy)acetic acid;RARECHEM AL BO 0389;P-CHLOROPHENOXYACETIC ACID;p-Monochlorophenoxy acetic acid;(2-chlorophenoxy)ethanoicacid;kyselina4-chlorfenoxyoctova;Marks 4-cpa;marks4-cpa |
| CAS: | 122-88-3 |
| MF: | C8H7ClO3 |
| MW: | 186.59 |
| EINECS: | 204-581-3 |
| Product Categories: | Organic acids;Phenoxyacetic Acids and Alcohols (substituted);Auxins;Biochemistry;Plant Growth Regulators;PLANT GROWTH REGULATOR;Pharmaceutical Raw Materials |
| Mol File: | 122-88-3.mol |
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4-Chlorophenoxyacetic acid Chemical Properties
| Melting point | 157-159 °C |
| Boiling point | 266.91°C (rough estimate) |
| density | 1.3245 (rough estimate) |
| refractive index | 1.5250 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 957mg/l |
| form | crystalline |
| pka | pK1: 3.10 (25°C) |
| color | White to light beige |
| Water Solubility | 848mg/L(25 ºC) |
| BRN | 1211804 |
| Major Application | agriculture
environmental |
| InChI | 1S/C8H7ClO3/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5H2,(H,10,11) |
| InChIKey | SODPIMGUZLOIPE-UHFFFAOYSA-N |
| SMILES | OC(=O)COc1ccc(Cl)cc1 |
| LogP | 2.250 |
| CAS DataBase Reference | 122-88-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Chlorophenoxyacetic acid(122-88-3) |
| EPA Substance Registry System | 4-Chlorophenoxyacetic acid (122-88-3) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-R22 |
| Safety Statements | 22-24/25 |
| RIDADR | 2811 |
| WGK Germany | 1 |
| RTECS | AG0175000 |
| F | 21 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29189090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Hazardous Substances Data | 122-88-3(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: 850mg/kg |
4-Chlorophenoxyacetic acid Usage And Synthesis
| Chemical Properties | white to light beige powder |
| Uses | 4-chlorophenoxy acetic acid (4-CPA), a chlorine derivative of phenoxyacetic acid (PA), is a plant growth regulator used as a herbicide. |
| Uses | 2-(4-Chlorophenoxy)acetic Acid is used in the synthesis of a new class of hypoxia-inducible factor-1 inhibitors. |
| Definition | ChEBI: A chlorophenoxyacetic acid that is phenoxyacetic acid carrying a chloro substituent at position 4. |
| General Description | 4-Chlorophenoxyacetic acid is a herbicide. Degradation of 4-chlorophenoxyacetic acid in aqueous medium by advanced electrochemical oxidation processes, using an undivided cell containing a Pt anode has been reported. |
| Hazard | Moderately toxic; mutagen. |
| Biochem/physiol Actions | 4-Chlorophenoxyacetic acid is a synthetic auxin, that is used to induce parthenocarpic ovary growth on flowers of wild type plants. |
| Safety Profile | Moderately toxic by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. |
| Purification Methods | Crystallise the acid from EtOH. It is a plant growth substance and a herbicide. [Beilstein 6 IV 845.] |
4-Chlorophenoxyacetic acid Preparation Products And Raw materials
| Raw materials | Iodine-->Chloroacetic acid-->4-Chlorophenol-->Phenoxyacetic acid |
| Preparation Products | 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate-->?4-Chlorophenoxyacetic acid sodium salt-->Meclofenoxate hydrochloride-->2,4,6-TRICHLOROPHENOXYACETIC ACID-->2-(p-Chlorophenoxy)-N-[3-(dimethylamino)propyl]acetamide-->Acetamide, 2-(4-chlorophenoxy)-N-methoxy-N-methyl--->CHEMBRDG-BB 7119439-->1,3,4-Thiadiazol-2-aMine, 5-[(4-chlorophenoxy)Methyl]--->2-(4-CHLORO-PHENOXY)-1-PIPERAZIN-1-YL-ETHANONE |
