Introduction：Basic information about 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide CAS 300851-67-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Basic information
| Product Name: | 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide |
| Synonyms: | 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide;4-CMTB;2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide;2-(4-Chloro-phenyl)-3-methyl-N-thiazol-2-yl-butyramide;Benzeneacetamide, 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-;4-CMTB >=98% (HPLC);short-chain,4 CMTB,fatty,acids,ECL2,FFAR,Free Fatty Acid Receptor,4CMTB,GPCRs,4-CMTB,ago-allosteric,free,ligand,Inhibitor,inhibit;4-CMTB, 10 mM in DMSO |
| CAS: | 300851-67-6 |
| MF: | C14H15ClN2OS |
| MW: | 294.8 |
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| Product Categories: | |
| Mol File: | 300851-67-6.mol |
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4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Chemical Properties
| Melting point | 191-192 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4)) |
| density | 1.290±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥10mg/mL |
| pka | 8.88±0.50(Predicted) |
| form | powder |
| color | white to beige |
| InChI | 1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18) |
| InChIKey | AZYDQCGCBQYFSE-UHFFFAOYSA-N |
| SMILES | CC(C)C(C(=O)Nc1nccs1)c2ccc(Cl)cc2 |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2 |
4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Usage And Synthesis
| Uses | 4-CMTB has been used as an allosteric agonist for the free fatty acid receptor 2 (FFAR2) in human lung carcinoma (A549) cells for cell viability assay and Influenza A virus (IAV) internalization studies. |
| Definition | ChEBI: 2-(4-chlorophenyl)-3-methyl-N-(2-thiazolyl)butanamide is a member of acetamides. |
| Biological Activity | 4-CMTB is a phenylacetamide compound th at acts as an allosteric modulator for the activity of short-chain fatty acid ligand in the FFA2 receptor.', '4-CMTB is a potent allosteric agonist of free fatty acid receptor 2 (FFA2). |
| storage | Store at +4°C |
4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide Preparation Products And Raw materials
