6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one CAS 60796-64-7

Introduction：Basic information about 6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one CAS 60796-64-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one Basic information

• Product Name: 6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one
• Synonyms: 6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one;Norbraylin;rbraylin;2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 6-hydroxy-8,8-dimethyl-;6-Hydroxy-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one
• CAS: 60796-64-7
• MF: C14H12O4
• MW: 244.24
• Product Categories: Coumarins
• Mol File: 60796-64-7.mol

6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one Chemical Properties

• Boiling point: 471.1±45.0 °C(Predicted)
• density: 1.319±0.06 g/cm3(Predicted)
• pka: 8.34±0.40(Predicted)

6-Hydroxy-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one Usage And Synthesis

Uses

Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC50 value of 7.15 μM[1].

IC 50

PDE4D2: 7.15 μM (IC₅₀)

References

[1] Lin Chen, et al. (P)/(M)-corinepalensin A, a pair of axially chiral prenylated bicoumarin enantiomers with a rare C-5C-5' linkage from the twigs of Coriaria nepalensis. Phytochemistry. 2018 May;149:140-145. DOI:10.1016/j.phytochem.2018.02.012