Introduction：Basic information about 6-METHOXY-2-BENZOXAZOLINONE CAS 532-91-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
6-METHOXY-2-BENZOXAZOLINONE Basic information
| Product Name: | 6-METHOXY-2-BENZOXAZOLINONE |
| Synonyms: | JRH-04701, 6-Methoxybenzo[d]oxazol-2(3H)-one, 97%;6-Methoxy-2,3-dihydrobenzoxazole-2-one;6-Methoxybenzoxazol-2(3H)-one;6-methoxy-3H-1,3-benzoxazol-2-one;6-Methoxy-2-benzoxazoline;6-Methoxy-3H-benzoxazol-2-one;6-Methoxy benzoxazol-2-one;6-METHOXY-2-BENZOXAZOLININE |
| CAS: | 532-91-2 |
| MF: | C8H7NO3 |
| MW: | 165.15 |
| EINECS: | |
| Product Categories: | Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Oxazoles;Building Blocks;Heterocyclic Building Blocks;Oxazolines/Oxazolidines;Heterocyclic Compounds |
| Mol File: | 532-91-2.mol |
|
6-METHOXY-2-BENZOXAZOLINONE Chemical Properties
| Melting point | 151-156 °C(lit.) |
| Boiling point | 292.97°C (rough estimate) |
| density | 1.3450 (rough estimate) |
| refractive index | 1.5468 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetone, Dichloromethane, Methanol, Tetrahydrofuran |
| form | Solid |
| pka | 8.73±0.70(Predicted) |
| color | light tan |
| BRN | 141041 |
| InChI | 1S/C8H7NO3/c1-11-5-2-3-6-7(4-5)12-8(10)9-6/h2-4H,1H3,(H,9,10) |
| InChIKey | MKMCJLMBVKHUMS-UHFFFAOYSA-N |
| SMILES | COc1ccc2NC(=O)Oc2c1 |
Safety Information
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | DM5275200 |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
6-METHOXY-2-BENZOXAZOLINONE Usage And Synthesis
| Chemical Properties | Off-white powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Imperata cylindrica, reed rhizome, seed kernel and root of Coix lacryma. |
| Uses | 6-Methoxybenzoxazolinone is an intermdiate in the synthesis of DIMBOA-4-O-β-D-glucuronide which is a metabolite of DIMBOA which acts as an antifungal and antialgal agent in crops. The benzoxazinone group within the structure allows for these effects. |
| Definition | ChEBI: Coixol is a benzoxazole. |
| Synthesis Reference(s) | Synthetic Communications, 23, p. 343, 1993 DOI: 10.1080/00397919308009786 |
| General Description | 6-Methoxy-2-benzoxazolinone (MBOA) is obtained by reacting 2-amino-5-methoxyphenol hydrochloride with urea. MOBA is a naturally occurring auxin-inhibiting substance present in maize shoots. |
| in vivo | | Animal Model: | 9–12 weeks, Sprague Dawley (SD) male rats[3] | | Dosage: | 25, 50 mg/kg | | Administration: | P.o. | | Result: | Decreased the blood glucose levels significantly, improved glucose tolerance. |
|
6-METHOXY-2-BENZOXAZOLINONE Preparation Products And Raw materials
