7-Hydroxy-5-methyl-1,3,4-triazaindolizine CAS 2503-56-2
Introduction：Basic information about 7-Hydroxy-5-methyl-1,3,4-triazaindolizine CAS 2503-56-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Basic information
| Product Name: | 7-Hydroxy-5-methyl-1,3,4-triazaindolizine |
| Synonyms: | 2,4]Triazolo[1,5-a]pyrimidin-7-ol,5-methyl-[1;5-a)pyrimidin-7-ol,5-methyl-s-triazolo(;5-Methyl-7-hydroxy-1,3,4-triazindolizine;5-Methyl-s-trazolo[1,5-]pyrimidin-7-ol;Methyl hydroxytriazaindolizine;5-Methyl-s-triazolo[1,5-a]pyrimidin-7-ol,98%;5-Methyl (1,2,4)trizolo(1,5-α)pyrimidin-7-ol;5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-7-ol |
| CAS: | 2503-56-2 |
| MF: | C6H6N4O |
| MW: | 150.14 |
| EINECS: | 219-706-7 |
| Product Categories: | Industrial/Fine Chemicals;Benzotriazoles;Building Blocks;C-C Bond Formation;Chemical Synthesis;Heterocyclic Building Blocks;Others;Synthetic Reagents |
| Mol File: | 2503-56-2.mol |
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Chemical Properties
| Melting point | 280-283 °C(lit.) |
| Boiling point | 271.66°C (rough estimate) |
| density | 1.3471 (rough estimate) |
| vapor pressure | 0-0Pa at 20-25℃ |
| refractive index | 1.6700 (estimate) |
| storage temp. | 2-8°C |
| pka | 1.14±0.53(Predicted) |
| form | solid |
| color | White to Almost white |
| Water Solubility | INSOLUBLE IN COLD WATER |
| BRN | 609440 |
| InChI | 1S/C6H6N4O/c1-4-2-5(11)10-6(9-4)7-3-8-10/h2-3,11H,1H3 |
| InChIKey | ZUIVNYGZFPOXFW-UHFFFAOYSA-N |
| SMILES | Cc1cc(O)n2ncnc2n1 |
| LogP | -1.4 at 19℃ and pH7.1 |
| CAS DataBase Reference | 2503-56-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyrimidin-7-ol, 5-methyl-s-triazolo-[1,5-a]-(2503-56-2) |
| EPA Substance Registry System | [1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl- (2503-56-2) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 1 |
| RTECS | XZ6133300 |
| F | 9 |
| Hazard Note | Harmful |
| TSCA | TSCA listed |
| HS Code | 2933998090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Toxicity | mouse,LD50,intravenous,> 450mg/kg (450mg/kg),Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 597, 1977. |
| Chemical Properties | 7-Hydroxy-5-methyl-1,3,4-triazaindolizine is white fine crystalline powder |
| Uses | Reactant for the synthesis of: • ;Ruthenium(II)-Hmtpo complexes1• ;Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5 |
| Uses | Reactant for the synthesis of:
Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles Investigations of the pharmacological activity caused by binding to HIV TAR RNA Additive to study the space charge layer in silver bromide microcrystals |
| reaction suitability | reaction type: C-C Bond Formation |
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Preparation Products And Raw materials
| Raw materials | 3-Amino-1,2,4-Triazole-->Ethyl acetoacetate |
