7-HYDROXYCOUMARIN GLUCOSIDE CAS 93-39-0
7-HYDROXYCOUMARIN GLUCOSIDE Basic information
| Product Name: | 7-HYDROXYCOUMARIN GLUCOSIDE |
| Synonyms: | Umbelliferone, beta-D-glucopyranoside;HYDROXYCOUMARIN-7-GLUCOSIDE, 7-(SKIMMIN)(P);7-(beta-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one;6‘-succinylskimmin;SKIMMIN;UMBELLIFERONE GLUCOSIDE;7-(β-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one;7-(β-D-Glucopyranosyloxy)coumarin |
| CAS: | 93-39-0 |
| MF: | C15H16O8 |
| MW: | 324.28 |
| EINECS: | 200-158-5 |
| Product Categories: | Coumarins |
| Mol File: | 93-39-0.mol |
7-HYDROXYCOUMARIN GLUCOSIDE Chemical Properties
| Melting point | 221-222℃ |
| alpha | D18 -80° (c = 10 in pyridine) |
| Boiling point | 422.63°C (rough estimate) |
| density | 1.588 |
| refractive index | 1.5500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 1mg/mL |
| form | Solid |
| pka | 12.73±0.70(Predicted) |
| color | White to off-white |
| Major Application | metabolomics vitamins, nutraceuticals, and natural products |
| InChI | 1S/C15H16O8/c16-6-10-12(18)13(19)14(20)15(23-10)21-8-3-1-7-2-4-11(17)22-9(7)5-8/h1-5,10,12-16,18-20H,6H2/t10-,12-,13+,14-,15-/m1/s1 |
| InChIKey | VPAOSFFTKWUGAD-TVKJYDDYSA-N |
| SMILES | O[C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O)CO)OC2=CC(O3)=C(C=C2)C=CC3=O |
Safety Information
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Tripterygium wilfordii, Artemisia capillaris, and Glechoma longituba. |
| Uses | Skimmin is a useful research chemical with neuroprotective effects. |
| Definition | ChEBI: Skimmin is a member of coumarins and a glycoside. |
| Biological Activity | Renal protecting, anti-inflammation. |
| Synthesis | A method for the preparation of 7-hydroxycoumarin glucoside, characterized in that said method consists of the following steps: (1) take the whole herb of horseshoe gold, at room temperature with acetone solution tissue crushing extraction 3 times, each time for 10-30 minutes, the combined extract, concentrated under reduced pressure to the extract; (2) extract the extract with the proportion of 10:1 ethyl acetate - methanol mixed solution for 15-18 countercurrent extraction, the combined extract, decompression Recovery of solvent, the extract; (3) the extract will be dispersed with water, through the polyamide resin column, 30-60% ethanol elution, eluent concentration of the crude product; (4) the crude product will be dissolved in methanol, sampling to the silica gel mesh number of 200-300 of the medium-pressure chromatography column, eluted with a mixture of methanol - dichloromethane, the collection of the target components of the section of the eluent, filtration, concentration and low-temperature drying that is to obtain 7-hydroxycoumarin glucoside. |
7-HYDROXYCOUMARIN GLUCOSIDE Preparation Products And Raw materials
