Introduction：Basic information about Aceglatone CAS 642-83-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Aceglatone Basic information
| Product Name: | Aceglatone |
| Synonyms: | Aceglatone;(2-acetyloxy-3,7-dioxo-4,8-dioxabicyclo[3.3.0]oct-6-yl) acetate;2-O,5-O-Diacetyl-D-glucaric acid 1,4:6,3-dilactone;2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone;2,5-di-O-Acetyl-D-glucosaccharo-(1→4:6→3)-dilactone;D-Glucaric acid, di-γ-lactone, 2,5-diacetate;Furo[3,2-b]furan, D-glucaric acid deriv.;Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI) |
| CAS: | 642-83-1 |
| MF: | C10H10O8 |
| MW: | 258.18 |
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| Mol File: | 642-83-1.mol |
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Aceglatone Chemical Properties
| Melting point | 185-186° (Hirasaka) |
| density | 1.49 |
Safety Information
Aceglatone Usage And Synthesis
| Uses | Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1]. |
| Definition | ChEBI: Aceglatone is an organic molecular entity. |
| References | [1] Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats DOI:10.3892/mmr_00000022 |
Aceglatone Preparation Products And Raw materials
