Introduction：Basic information about ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT CAS 74804-12-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Basic information
| Product Name: | ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT |
| Synonyms: | ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT;ATP MAGNESIUM SALT;ATP-MG;adenosine 5'-triphosphate magnesium*from equine M;ADENOSINE 5'-TRIPHOSPHATE MAGNESIUMFROM BACTERIAL;ATP MAGNESIUM;adenosine 5'-triphosphate magnesium salt trihydrate;Adenosine 5′-triphosphate magnesium salt,ATP magnesium salt |
| CAS: | 74804-12-9 |
| MF: | C10H18MgN5O13P3 |
| MW: | 533.5 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 74804-12-9.mol |
|
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Chemical Properties
| Melting point | >300°C |
| storage temp. | -20°C |
| solubility | H2O: 50 mg/mL |
| form | Solid |
| color | White to Pale Yellow |
| biological source | bacterial |
| Water Solubility | H2O: 50mg/mL |
| Stability: | Hygroscopic |
| InChIKey | CPGAIACWYFBIFN-UHFFFAOYSA-N |
| SMILES | [Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-68/20/21/22 |
| Safety Statements | 36/37 |
| WGK Germany | 1 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | STOT SE 2 |
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Usage And Synthesis
| Uses | Adenosine 5′-triphosphate magnesium salt has been used:
- as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
- as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
- as a component in action potential intracellular solution
|
| Biochem/physiol Actions | Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. |
| in vivo | ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4].
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo[4].
| Animal Model: | Four-week-old Kunming mice (18-22 g)[4] | | Dosage: | 50 mg/kg | | Administration: | Intraperitoneal injection, before bacterial (E. coli) challenge | | Result: | Protected mice from bacterial infection. |
|
| IC 50 | Human Endogenous Metabolite |
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Preparation Products And Raw materials
