Introduction：Basic information about alpha-Asarone CAS 2883-98-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
alpha-Asarone Basic information
| Product Name: | alpha-Asarone |
| Synonyms: | alpha-Asarion;alpha-Asaron;ASARONE;ASARONE, A-;(e)-1,2,4-trimethoxy-5-(1-propenyl)benzene;A-ASARONE;ALPHA-ASARONE;ALPHA-ASARONE (PHENOL DERIVATIVE) |
| CAS: | 2883-98-9 |
| MF: | C12H16O3 |
| MW: | 208.25 |
| EINECS: | 220-743-6 |
| Product Categories: | API;Aromatic Ethers |
| Mol File: | 2883-98-9.mol |
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alpha-Asarone Chemical Properties
| Melting point | 57-61 °C(lit.) |
| Boiling point | 296 °C(lit.) |
| density | 1.1227 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Soluble in chloroform, methanol. |
| form | Solid |
| color | White to Off-White |
| Sensitive | Light Sensitive |
| λmax | 312nm(EtOH)(lit.) |
| BRN | 1910606 |
| InChI | InChI=1S/C12H16O3/c1-5-6-9-7-11(14-3)12(15-4)8-10(9)13-2/h5-8H,1-4H3/b6-5+ |
| InChIKey | RKFAZBXYICVSKP-AATRIKPKSA-N |
| SMILES | C1(OC)=CC(/C=C/C)=C(OC)C=C1OC |
| LogP | 3.406 (est) |
| CAS DataBase Reference | 2883-98-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Asarone(2883-98-9) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | DC2975000 |
| HS Code | 29093090 |
| Storage Class | 13 - Non Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
| Hazardous Substances Data | 2883-98-9(Hazardous Substances Data) |
| Toxicity | bird - wild,LD50,oral,750mg/kg (750mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. |
alpha-Asarone Usage And Synthesis
| Chemical Properties | Asarone is a colorless tryst. M.P. 66-67℃. B.P. 296℃. Pure Asarone is reported to be virtuallyodorless and tasteless. However, available samples of the material have in experimentsshown perceptible influence upon the odor ofcompositions containing lower boiling perfume materials. Insoluble in water, soluble in alcohol andoils. |
| Uses | α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action. |
| Application | Asarone has been suggested for use asa fixative-blender with Patchouli-like odorcharacter. |
| Preparation | 1) by isolation from the essential oil ofAcorus Calamus.
2) synthesis. by reduction of Asaraldehyde. |
| Definition | ChEBI: The trans-isomer of asarone. |
| General Description | Asarones are toxic morphogenetic agents. It is also known for its chemosterlant and oviposition stimulant properties. Naturally it can be extracted from Acorus calamus. α-Asarone is considered as growth inhibitor. This isomer acts as antifeedant with less toxicity. |
alpha-Asarone Preparation Products And Raw materials
| Raw materials | BETA-ASARONE-->Ethyltriphenylphosphonium bromide-->2,4,5-TRIMETHOXYLPRORIOPHENONE-->2,4,5-Trimethoxybenzaldehyde |
