Introduction：Basic information about ansamitocin P-3 CAS 66584-72-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
ansamitocin P-3 Basic information
| Product Name: | ansamitocin P-3 |
| Synonyms: | 2'-De(acetylmethylamino)-2'-methylmaytansine;2'-De[acetyl(methyl)amino]-2'-methylmaytansine;Anasamitocin P-3;Maytansinol isobutyrate;Nsc292222;Tam 330;Tam-330;Ansamitosin P 3 |
| CAS: | 66584-72-3 |
| MF: | C32H43ClN2O9 |
| MW: | 635.14 |
| EINECS: | |
| Product Categories: | Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Microtobule Inhibitors |
| Mol File: | 66584-72-3.mol |
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ansamitocin P-3 Chemical Properties
| Melting point | 190-192℃ |
| Boiling point | 833.1±65.0 °C(Predicted) |
| density | 1.29 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: 100 mg/mL (157.45 mM);Ethanol: 55 mg/mL (86.60 mM) |
| pka | 9.82±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Water: Insoluble |
| InChIKey | OPQNCARIZFLNLF-VLSFGAMINA-N |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | OQ2293000 |
| HS Code | 2941900000 |
ansamitocin P-3 Usage And Synthesis
| Description | Ansamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation. |
| Uses | Ansamitocin P-3 is an antitumor agent that binds to cell division protein FtsZ in Actinosynnema pretiosum. |
| Definition | ChEBI: A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity. |
| IC 50 | Maytansinoids |
ansamitocin P-3 Preparation Products And Raw materials
