Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) CAS 1366000-58-9

Introduction：Basic information about Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) CAS 1366000-58-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) Basic information

• Product Name: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate)
• Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate);Atrial Natriuretic Peptide (ANP) (128), human, porcine Acetate,Atrial Natriuretic Peptide (ANP) (1 28), human, porcine Acetate;ANP(1-28) Acetate (human, porcine);Atrial natriuretic factor (1-28) (human) acetate
• CAS: 1366000-58-9
• MF: C129H207N45O41S3
• MW: 3140.53
• Mol File: 1366000-58-9.mol

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) Chemical Properties

• storage temp.: Store at -20°C
• form: Solid
• color: White to off-white
• Water Solubility: 25mg/ml in Water
• Sequence: H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bridge: Cys7-Cys23)
• InChIKey: NYSSIVMKYRVLPL-CYAMPLDWNA-N

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine (Acetate) Usage And Synthesis

Uses

Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.

References

[1] Kohno M, et al. Atrial and brain natriuretic peptides inhibit the endothelin-1 secretory response to angiotensin II in porcine aorta. Circ Res. 1992 Feb;70(2):241-7. DOI:10.1161/01.res.70.2.241
[2] Kohno M, et al. Inhibition by atrial and brain natriuretic peptides of endothelin-1 secretion after stimulation with angiotensin II and thrombin of cultured human endothelial cells. J Clin Invest. 1991 Jun;87(6):1999-2004. DOI:10.1172/JCI115228
[3] Ballermann BJ, et al. Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli. J Clin Invest. 1985 Dec;76(6):2049-56. DOI:10.1172/JCI112207