Benzyldiphenylphosphine CAS 7650-91-1

Introduction：Basic information about Benzyldiphenylphosphine CAS 7650-91-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Benzyldiphenylphosphine Basic information

• Product Name: Benzyldiphenylphosphine
• Synonyms: Benzyldiphenylphosphine,98%;BENZYLDIPHENYLPHOSPHINE;Benzyldiphenylphosphine,99%;Diphenyl(phenylmethyl)phosphine;Diphenylbenzylphosphine;Benzyldiphenylphosphine,97%;Phosphine, diphenyl(phenylmethyl)-
• CAS: 7650-91-1
• MF: C19H17P
• MW: 276.31
• EINECS: 1312995-182-4
• Product Categories: organophosphorus ligand;Achiral Phosphine;Aryl Phosphine;Basic Phosphine LigandsCatalysis and Inorganic Chemistry;Catalysis and Inorganic Chemistry;Cross-Coupling;Phosphine Ligands;Phosphorus Compounds
• Mol File: 7650-91-1.mol

Benzyldiphenylphosphine Chemical Properties

• Melting point: 77-83 °C (lit.)
• Boiling point: 205-208 °C(Press: 1.5 Torr)
• storage temp.: Inert atmosphere,Room Temperature
• form: Powder
• color: White to off-white
• Water Solubility: Slightly soluble in water.
• Sensitive: Air Sensitive
• InChI: InChI=1S/C19H17P/c1-4-10-17(11-5-1)16-20(18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15H,16H2
• InChIKey: UZCPNEBHTFYJNY-UHFFFAOYSA-N
• SMILES: P(C1=CC=CC=C1)(C1=CC=CC=C1)CC1=CC=CC=C1

Safety Information

• Hazard Codes: Xn
• Risk Statements: 36/37/38-22
• Safety Statements: 37/39-26
• WGK Germany: 3
• HS Code: 29310099
• Storage Class: 11 - Combustible Solids

Benzyldiphenylphosphine Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

suzuki reaction

Uses

Employed as a catalyst for Suzuki cross-coupling and antiarthritic agent (inhibitor of cathepsin B). It is also used as catalyst in pharmaceutical research.

Preparation

An acetato-bridged binuclear cyclopalladated complex of benzyldiphenylphosphine, [{Pd(C6H4CH2PPh2)(O2CMe)}], could been obtained by the reaction between the phosphine and palladium(II) acetate[1].

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

References

[1] Katsuma Hiraki, Toshinobu Uchiyama, Yoshio Fuchita. “Cyclopalladation of benzyldiphenylphosphine by palladium(II) acetate.” Inorganica Chimica Acta 69 (1983): Pages 187-190.