BENZYLHYDRAZINE DIHYDROCHLORIDE CAS 20570-96-1
Introduction：Basic information about BENZYLHYDRAZINE DIHYDROCHLORIDE CAS 20570-96-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
BENZYLHYDRAZINE DIHYDROCHLORIDE Basic information
| Product Name: | BENZYLHYDRAZINE DIHYDROCHLORIDE |
| Synonyms: | BENZYL HYDRAZINE DI HCL;BENZYLHYDRAZINE DIHYDROCHLORIDE;Benzylhydrazine2HCl;Hydrazine, benzyl, dihydrochloride.;BZHDH;benzyl-hydrazindihydrochloride;Benzylhydrazine dihydrochloride,97%;BENZYLHYDRAZINE DIHY |
| CAS: | 20570-96-1 |
| MF: | C7H10N2.2HCl |
| MW: | 195.09 |
| EINECS: | 243-887-1 |
| Product Categories: | Pharmaceutical intermediate;Hydrazines;Nitrogen Compounds;Organic Building Blocks |
| Mol File: | 20570-96-1.mol |
BENZYLHYDRAZINE DIHYDROCHLORIDE Chemical Properties
| Melting point | 143-145 °C (dec.)(lit.) |
| Boiling point | 149.5℃ at 95.5kPa |
| density | 0.628g/cm3 at 23℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Powder |
| color | Slightly yellow to beige |
| Water Solubility | Insoluble in water. |
| BRN | 3688990 |
| InChI | InChI=1S/C7H10N2.2ClH/c8-9-6-7-4-2-1-3-5-7;;/h1-5,9H,6,8H2;2*1H |
| InChIKey | MSJHOJKVMMEMNX-UHFFFAOYSA-N |
| SMILES | N(CC1=CC=CC=C1)N.[H]Cl.[H]Cl |
| Dissociation constant | 0.001-0.001 at 23℃ |
| CAS DataBase Reference | 20570-96-1(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | MU8540000 |
| F | 10 |
| TSCA | Yes |
| HazardClass | IRRITANT |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 29280000 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Toxicity | LD50 ipr-mus: 11 mg/kg JMCMAR 18,20,75 |
| Chemical Properties | slightly yellow to beige powder |
| Uses | Benzylhydrazine dihydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. |
| Safety Profile | Poison by intraperitoneal route.Questionable carcinogen with experimental neoplastigenicdata. When heated to decomposition it emits very toxicfumes of HCl and NOx. |
| Synthesis | Step 1: Tert-butyl hydrazinecarboxylate was reacted in acetone with MgSO4 and HOAc. The mixture was heated to reflux. After cooling and filtration, concentration gave a white solid (1). Step 2: Compound (1) was dissolved in toluene with solid KOH and a phase-transfer catalyst. Benzyl bromide was added at 50??C. The temperature was then raised to 80??C. After completion, the mixture was washed, dried, and concentrated to give an oil (2f). Step 3: 2N HCl was added to a THF solution of (2f). The mixture was heated at reflux. After concentration and drying, the dihydrochloride salt (3f) was obtained by filtration. |
BENZYLHYDRAZINE DIHYDROCHLORIDE Preparation Products And Raw materials
| Raw materials | Methanol-->Toluene-->Palladium-->Hydrazine hydrate-->Benzyl chloride-->Benzaldehyde |
| Preparation Products | ISOCARBOXAZID (200 MG)-->Benzylhydrazine-->ethyl 5-amino-1-benzyl-3-methyl-1H-pyrazole-4-carboxylate-->1-benzyl-6,7-dihydro-1H-indazol-4(5H)-one-->2-benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one |
