Introduction：Basic information about BISPYRAZOLONE CAS 7477-67-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
BISPYRAZOLONE Basic information
| Product Name: | BISPYRAZOLONE |
| Synonyms: | BIS(3-METHYL-1-PHENYL-5-PYRAZOLONE);BIS(1-PHENYL-3-METHYL-5-PYRAZOLONE);BISPYRAZOLONE;LABOTEST-BB LT00008461;4,4'-BIS(3-METHYL-1-PHENYL-5-PYRAZOLONE);4,4'-BIS(1-PHENYL-3-METHYL-5-PYRAZOLONE);3,3-DIMETHYL-1,1-DIPHENYL-(4,4-BI-2-PYRAZOLINE)-5,5-DIONE;3,3'-DIMETHYL-1,1'-DIPHENYL-[4,4'-BI-2-PYRAZOLINE]-5,5'-DIONE |
| CAS: | 7477-67-0 |
| MF: | C20H18N4O2 |
| MW: | 346.38 |
| EINECS: | 231-282-5 |
| Product Categories: | Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocyclic Compounds |
| Mol File: | 7477-67-0.mol |
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BISPYRAZOLONE Chemical Properties
| Melting point | 355 °C |
| Boiling point | 481.12°C (rough estimate) |
| density | 1.31 |
| refractive index | 1.6620 (estimate) |
| storage temp. | Refrigerator |
| solubility | formic acid: 50 mg/mL, clear, yellow |
| pka | 2.15±0.70(Predicted) |
| form | crystalline |
| color | tan |
| BRN | 572787 |
| InChI | 1S/C20H18N4O2/c1-13-17(19(25)23(21-13)15-9-5-3-6-10-15)18-14(2)22-24(20(18)26)16-11-7-4-8-12-16/h3-12,17-18H,1-2H3 |
| InChIKey | FORCWSNQDMPPOC-UHFFFAOYSA-N |
| SMILES | CC1=NN(c2ccccc2)C(=O)C1C3C(C)=NN(c4ccccc4)C3=O |
| CAS DataBase Reference | 7477-67-0(CAS DataBase Reference) |
| EPA Substance Registry System | [4,4'-Bi-3H-pyrazole]-3,3'-dione, 2,2',4,4'-tetrahydro-5,5'-dimethyl-2,2'-diphenyl- (7477-67-0) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 29331990 |
| Storage Class | 11 - Combustible Solids |
BISPYRAZOLONE Usage And Synthesis
| Chemical Properties | off-white to cream-yellowish crystalline powder |
| Uses | Bispyrazolone is an impurity of Edaravone (E335000). |
| Uses | It is applied as a reagent for the detection and determination of cyanide. It is also used in an experimental procedure, done in order to remove linamarin in starch from cassava roots, by using plant cell wall-degrading enzymes, xylanase and cellulase. It was also used for spectrophotometric determination and quantization of urea in urine samples. It is also used in assay of cyanogenic compounds and determination of ammonia. |
BISPYRAZOLONE Preparation Products And Raw materials
| Raw materials | Acetic acid-->N-Bromosuccinimide-->Ethyl acetoacetate-->Sodium acetate trihydrate-->Phenylhydrazine-->1H-Pyrazol-5-ol, 3-methyl-4-nitroso-1-phenyl--->4-bromo-3-methyl-1-phenyl-pyrazolin-5-one-->Edaravone-->1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one-->Ethanol-->Selenium dioxide-->5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one |
| Preparation Products | 4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-1,2-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one |
