Boldenone CAS 846-48-0
Introduction：Basic information about Boldenone CAS 846-48-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Boldenone Basic informationDescription Sources
| Product Name: | Boldenone |
| Synonyms: | 17-beta-hydroxy-17-alpha-1,4-androstadien-3-one;17-beta-hydroxy-androsta-4-dien-3-one;dehydrotestosterone;17-hydroxy-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one;Boldenone(846-48-0);Boldenone (eq);High purity 99% Boldenone powder;Testosterone Impurity 8(Testosterone EP Impurity H) |
| CAS: | 846-48-0 |
| MF: | C19H26O2 |
| MW: | 286.41 |
| EINECS: | 212-686-0 |
| Product Categories: | boldenone;API;Steroid and Hormone;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;1 |
| Mol File: | 846-48-0.mol |
Boldenone Chemical Properties
| Melting point | 164-166°C |
| alpha | D25 +25° (in chloroform) |
| Boiling point | 368.77°C (rough estimate) |
| density | 1.0655 (rough estimate) |
| refractive index | 1.4709 (estimate) |
| storage temp. | Controlled Substance, -20°C Freezer |
| solubility | DMF: 25 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml |
| pka | 15.05±0.60(Predicted) |
| form | A crystalline solid |
| Water Solubility | 57.1mg/L at 20℃ |
| Major Application | forensics and toxicology pharmaceutical (small molecule) |
| InChI | InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3 |
| InChIKey | RSIHSRDYCUFFLA-KRHBYBJCNA-N |
| SMILES | [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,10,12,16,18,21,r| |
| CAS DataBase Reference | 846-48-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Boldenone(846-48-0) |
Safety Information
| Hazard Codes | F,Xn |
| Risk Statements | 11-20/21/22-36 |
| Safety Statements | 16-36/37 |
| WGK Germany | WGK 3 |
| RTECS | BV7994400 |
| HS Code | 29372900 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Aquatic Chronic 3 Carc. 2 Lact. Repr. 1A |
| Description | Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects. |
| Sources | https://en.wikipedia.org/wiki/Boldenone_undecylenate https://en.wikipedia.org/wiki/Boldenone https://www.drugs.com/vet/equipoise.html https://www.steroidal.com/steroid-profiles/equipoise/ https://www.evolutionary.org/equipoise-boldenone-undecylenate |
| Description | Boldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications. |
| Chemical Properties | Crystalline Solid |
| Uses | Boldenone is an anabolic steroid. Controlled substance. |
| Uses | Controlled substance. Anabolic steroid |
| Definition | ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use. |
| Brand name | Equipoise [Veterinary] (Fort DodgeAnimal Health). |
| Synthesis | Boldenone is obtained by reacting Testosterone with tert-butyldimethylsilyl chloride in the presence of DDQ. Experimental Procedure: 29.0 g Testosterone was dissolved in 220 ml dioxan/THF 8:2 and cooled to 0°C on ice. After cooling down a solution of tert-butyldimethylsilyl chloride (46.0 g in 100 ml dioxan/THF 8:2) was added dropwise and stirred for 90 min at 0°C. Then a suspension of 32.0 g of DDQ in 200ml dioxan/THF 8:2 was added in 4 equal portions over a period of 4 h. The reaction mixture was stirred for additional 12 h within coming from 0°C to room temperature.The resulting suspension was then filtered over Celite and rinsed with 300 ml THF. The filtrate was evaporated and brown oil was obtained. The oil was diluted in 1500 ml DCM and washed with 500 ml of 5% aqueous sodium hydroxide. The yellow organic phase was washed with 400 ml water and 400 ml saturated sodium chloride solution, before drying over magnesium sulfate. After evaporation, the crude product was chromatographed on silica gel by using hexane-ethyl acetate (3:7), followed by a recrystallization in ethyl acetate. 16.50 g of Boldenone was obtained as an amber solid (58%). |
| References | [1] C SAUDAN. Testosterone and doping control.[J]. British Journal of Sports Medicine, 2006, 40 Suppl 1: i21-4. DOI: 10.1136/bjsm.2006.027482 |
Boldenone Preparation Products And Raw materials
