BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II) CAS 251567-28-9

Introduction：Basic information about BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II) CAS 251567-28-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II) Basic information

• Product Name: BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II)
• Synonyms: [Pd(NCOC2H4CO)(PPh3)2Br];BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II);bromo(n-succinimidyl)bis(triphenylphosphine)palladium(ii);trans-Bromo(N-succinimidyl)bis(triphenylphosphine)palladium(II);trans-BroMo(N-succiniMidyl)bis(triphenylphosphine)palladiuM(II),97%;bromopalladium, pyrrolidin-1-ide-2,5-dione, triphenylphospho...;BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II)BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II);trans-Bromo(N-succinimidyl)bis(triphenylphosphine)palladium(II)
• CAS: 251567-28-9
• MF: C40H37BrNO2P2Pd
• MW: 812.01
• Mol File: 251567-28-9.mol

BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II) Chemical Properties

• Melting point: 223-228 °C (dec.) (lit.)
• form: solid
• InChI: 1S/2C18H15P.C4H5NO2.BrH.Pd/c2*1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;6-3-1-2-4(7)5-3;;/h2*1-15H;1-2H2,(H,5,6,7);1H;/q;;;;+2/p-2
• InChIKey: KYQYWUJRFOCJEW-UHFFFAOYSA-L
• SMILES: Br[Pd]N1C(=O)CCC1=O.c2ccc(cc2)P(c3ccccc3)c4ccccc4.c5ccc(cc5)P(c6ccccc6)c7ccccc7

Safety Information

• WGK Germany: 3
• Storage Class: 13 - Non Combustible Solids

BROMOBIS(PH3P)(N-SUCCINIMIDE)PD(II) Usage And Synthesis

Uses

trans-Bromo(N-succinimidyl)bis(triphenylphosphine)palladium(II) may be used in the following processes:

• As a catalyst for the preparation of 6-cyano-2-(3-fluoro-benzyl)-indole-1-carboxylic acid tert-butyl ester via Suzuki cross-coupling reaction between 1-boc-6-cyanoindole-2-boronic acid and 3-fluorobenzyl bromide. This method does not involve the use of strong bases or toxic reagents and also the use of this catalyst minimizes protodeboronation.
• As a precatalyst for the Suzuki-Miyaura cross-coupling reaction between alkenyl tosylates and alkenyl MIDA boronates in the absence of phosphine ligands. For less activated alkenyl tosylate, the addition of tricyclohexylphosphine tetrafluoroborate improves the reactivity.

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Cross Couplings
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst