Introduction:Basic information about CHARYBDOTOXIN CAS 95751-30-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
CHARYBDOTOXIN Basic information
| Product Name: | CHARYBDOTOXIN |
| Synonyms: | CHARYBDOTOXIN;CHARYBDOTOXIN, RECOMBINANT;CHARYBDOTOXIN, RECOMBINANT, E COLI;CHARYBDOTOXIN, LEIURUS QUINQUESTRIATUS HEBRAEUS;CHTX;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (DISULFIDE BRIDGE: 7-28,13-33 AND 17-35);PYR-PHE-THR-ASN-VAL-SER-CYS-THR-THR-SER-LYS-GLN-CYS-TRP-SER-VAL-CYS-GLN-ARG-LEU-HIS-ASN-THR-SER-ARG-GLY-LYS-CYS-MET-ASN-LYS-LYS-CYS-ARG-CYS-TYR-SER-OH |
| CAS: | 95751-30-7 |
| MF: | C176H277N57O55S7 |
| MW: | 4295.89 |
| EINECS: | |
| Product Categories: | Potassium channel;Ion Channels;peptide;Potassium Channel ModulatorsCell Signaling and Neuroscience;Potassium Channel ModulatorsPeptides for Cell Biology;Ion Channel Modulating Peptides;Monovalent Ion Channels;Scorpion;Toxins and Venoms;Voltage-gated Ion Channels |
| Mol File: | Mol File |
|
CHARYBDOTOXIN Chemical Properties
| RTECS | FL7535000 |
| storage temp. | -20°C |
| form | lyophilized powder |
| Water Solubility | Soluble to 1 mg/ml in water |
| Sequence | {Glp}-Phe-Thr-Asn-Val-Ser-Cys-Thr-Thr-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Gln-Arg-Leu-His-Asn-Thr-Ser-Arg-Gly-Lys-Cys-Met-Asn-Lys-Lys-Cys-Arg-Cys-Tyr-Ser (Disulfide bridge: Cys7-Cys28; Cys13-Cys33; Cys17-Cys35) |
| InChIKey | CNVQLPPZGABUCM-LIGYZCPXSA-N |
Safety Information
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
CHARYBDOTOXIN Usage And Synthesis
| Uses | Biochemical probe. |
| Uses | Charybdotoxin has been used:
- in the inhibition of endothelium-derived hyperpolarizing factor responses
- in electrophysiological studies, as calcium channel blockers
- as a transport inhibitor
|
| Biochem/physiol Actions | Potent and selective inhibitor of the Ca2+-activated K+ channel present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells. |
| storage | -20°C (desiccate) |
CHARYBDOTOXIN Preparation Products And Raw materials