Introduction：Basic information about D(-)-Norvaline CAS 2013-12-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
D(-)-Norvaline Basic information
| Product Name: | D(-)-Norvaline |
| Synonyms: | H-D-NVA-OH;H-D-NHCH[CH3(CH2)2]-COOH;H-D-NORVALINE;H-D-APE(2)-OH;D-NVal-OH;H-D-2-AMINOVALERIC ACID;D-Nva-OH;D-Nval |
| CAS: | 2013-12-9 |
| MF: | C5H11NO2 |
| MW: | 117.15 |
| EINECS: | 217-936-2 |
| Product Categories: | Amino Acids;Peptide;Norvaline [Nva];bc0001 |
| Mol File: | 2013-12-9.mol |
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D(-)-Norvaline Chemical Properties
| Melting point | >300 °C(lit.) |
| alpha | -24 º (c=5, 5N HCl) |
| Boiling point | 222.9±23.0 °C(Predicted) |
| density | 1.2000 (estimate) |
| refractive index | -25 ° (C=10, 6mol/L HCl) |
| storage temp. | Store at RT. |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| pka | 2.54±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| Optical Rotation | [α]20/D 24°, c = 10 in 5 M HCl |
| Water Solubility | SOLUBLE |
| Merck | 14,6716 |
| BRN | 1721161 |
| Major Application | peptide synthesis |
| Cosmetics Ingredients Functions | ANTISTATIC |
| InChI | 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1 |
| InChIKey | SNDPXSYFESPGGJ-SCSAIBSYSA-N |
| SMILES | CCC[C@@H](N)C(O)=O |
| CAS DataBase Reference | 2013-12-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-37/39-26 |
| WGK Germany | 3 |
| HS Code | 29224919 |
| Storage Class | 13 - Non Combustible Solids |
D(-)-Norvaline Usage And Synthesis
| Chemical Properties | white to off-white crystals or crystalline powder |
| Uses | D-Norvaline is used as a catalyst in the enantioselective α-bromination of carbonyl and 1,3-dicarbonyl compounds. D-Norvaline is also incorporated into jadomycins (a group of compounds that are widely used as antibiotics), ultimately producing compounds that have potential antiproliferative/anti-cancer properties. |
| Definition | ChEBI: D-2-aminopentanoic acid is a 2-aminopentanoic acid that has R-configuration. It has a role as an EC 6.1.1.4 (leucine--tRNA ligase) inhibitor. It is a D-alpha-amino acid and a 2-aminopentanoic acid. It is an enantiomer of a L-2-aminopentanoic acid. |
| reaction suitability | reaction type: solution phase peptide synthesis |
D(-)-Norvaline Preparation Products And Raw materials
| Raw materials | 2-Amino-pentanoic acid benzyl ester-->DL-Norvaline-->2-Amino-pentanamide HCl-->L-Norvaline |
| Preparation Products | D(-)-Glutamic acid |
