Dapagliflozin-d5 CAS 1204219-80-6

Introduction:Basic information about Dapagliflozin-d5 CAS 1204219-80-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Dapagliflozin-d5 Basic information

Product Name:Dapagliflozin-d5
Synonyms:Dapagliflozin-d5;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-(ethoxy-1,1,2,2,2-d5)phenyl]methyl]phenyl]-D-glucitol;[2H5]-Dapagliflozin;BMS-512148 D5;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol-D5;2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Dapagliflozin-d
CAS:1204219-80-6
MF:C21H20ClD5O6
MW:413.90340889
EINECS:
Product Categories:
Mol File:1204219-80-6.mol

Dapagliflozin-d5 Chemical Properties

Melting point >62°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability:Hygroscopic

Safety Information

Dapagliflozin-d5 Usage And Synthesis

DescriptionDapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.
UsesLabeled Dapagliflozin, Dapagliflozin-d5 can be intended for use as an internal standard for the quantification of Dapagliflozin by GC- or LC-mass spectrometry.
UsesDapagliflozin-D5 is a labelled analogue of Dapagliflozin (D185370), a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes.

Dapagliflozin-d5 Preparation Products And Raw materials

Raw materialsEthan-1,1,2,2,2-d5-ol, 1-(4-methylbenzenesulfonate)-->((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate-->4-(5-broMo-2-chlorobenzyl)phenol
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