Introduction:Basic information about Dapagliflozin-d5 CAS 1204219-80-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dapagliflozin-d5 Basic information
| Product Name: | Dapagliflozin-d5 |
| Synonyms: | Dapagliflozin-d5;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-(ethoxy-1,1,2,2,2-d5)phenyl]methyl]phenyl]-D-glucitol;[2H5]-Dapagliflozin;BMS-512148 D5;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol-D5;2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(ethoxy-d5)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Dapagliflozin-d |
| CAS: | 1204219-80-6 |
| MF: | C21H20ClD5O6 |
| MW: | 413.90340889 |
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| Mol File: | 1204219-80-6.mol |
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Dapagliflozin-d5 Chemical Properties
| Melting point | >62°C (dec.) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety Information
Dapagliflozin-d5 Usage And Synthesis
| Description | Dapagliflozin-d5 is a deuterium labeled Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor. |
| Uses | Labeled Dapagliflozin, Dapagliflozin-d5 can be intended for use as an internal standard for the quantification of Dapagliflozin by GC- or LC-mass spectrometry. |
| Uses | Dapagliflozin-D5 is a labelled analogue of Dapagliflozin (D185370), a selective sodium-glucose cotransporter-2 inhibitor that reduces renal glucose reabsorption and is used to treat patients with type 2 diabetes. |
Dapagliflozin-d5 Preparation Products And Raw materials
| Raw materials | Ethan-1,1,2,2,2-d5-ol, 1-(4-methylbenzenesulfonate)-->((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate-->4-(5-broMo-2-chlorobenzyl)phenol |