Introduction：Basic information about DHELWANGIN CAS 23800-56-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DHELWANGIN Basic information
| Product Name: | DHELWANGIN |
| Synonyms: | DHELWANGIN;4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one;4-Hydroxy-6-methyl-3-(4-methylpentanoyl)-2H-pyran-2-one;2H-Pyran-2-one,4-hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-;Autophagy,Apoptosis,Inhibitor,Pogostone,Bacterial,gram positive,gram negative,inhibit,corynebacterium xerosis;Pogostone, 10 mM in DMSO |
| CAS: | 23800-56-8 |
| MF: | C12H16O4 |
| MW: | 224.25 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 23800-56-8.mol |
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DHELWANGIN Chemical Properties
| Boiling point | 348.2±42.0℃ (760 Torr) |
| density | 1.185±0.06 g/cm3 (20 ºC 760 Torr) |
| Fp | 129.9±21.4℃ |
| storage temp. | 4°C, protect from light |
| solubility | DMF: 1.6mg/mL; DMSO: 3mg/mL; Ethanol: 3mg/mL; Ethanol:PBS (pH 7.2) (1:5): 0.16mg/mL |
| form | A solid |
| pka | 5.27±0.50(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C12H16O4/c1-7(2)4-5-9(13)11-10(14)6-8(3)16-12(11)15/h6-7,14H,4-5H2,1-3H3 |
| InChIKey | AJFJTORMMHWKFW-UHFFFAOYSA-N |
| SMILES | C1(=O)OC(C)=CC(O)=C1C(=O)CCC(C)C |
| LogP | 0.750 (est) |
Safety Information
DHELWANGIN Usage And Synthesis
| Uses | Pogostone is a useful research chemical. |
| Chemical Properties | Colorless needle crystals, easily soluble in ethyl acetate, methanol and ethanol, derived from patchouli volatile oil. |
| Uses | Pogostone is a useful research chemical exhibiting protective effects from Pogostemonis Herba against ethanol-induced gastric ulcer in rats. |
| Definition | ChEBI: Dhelwangin is an aromatic ketone. |
| in vivo | Pogostone ( intraperitoneal injection; 25, 50 and 100 mg/kg) shows antibacterial activity in vivo against Escherichia coli (E. coli) and MRSA. Ninety percent of the mice infected with E. coil could be protected at the concentrations of 50 and 100 mg/kg, and 60% of the mice at 25 mg/kg, while the rate of protection for the mice infected with MRSA was 60% and 50% at doses of 100 and 50 mg/kg, respectively[2]. |
DHELWANGIN Preparation Products And Raw materials
