Introduction：Basic information about Difloxacin CAS 98106-17-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Difloxacin Basic informationDescription Mechanism of action
| Product Name: | Difloxacin |
| Synonyms: | DIFLOXACIN;-1-piperazinyl)-4-oxo-;3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl;a56619;6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt;Difloxacin Hydrochloride Salt;6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid;DIFLOXACINHCL/MESYLATE |
| CAS: | 98106-17-3 |
| MF: | C21H19F2N3O3 |
| MW: | 399.39 |
| EINECS: | |
| Product Categories: | Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents |
| Mol File: | 98106-17-3.mol |
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Difloxacin Chemical Properties
| Melting point | 279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5)) |
| Boiling point | 595.5±50.0 °C(Predicted) |
| density | 1.409±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 6.17±0.41(Predicted) |
| color | White to Pale Yellow |
| CAS DataBase Reference | 98106-17-3(CAS DataBase Reference) |
Safety Information
Difloxacin Usage And Synthesis
| Description | Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin. |
| Mechanism of action | Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. |
| Physical properties | Whtie-Cream to Yellowish Crystalline Powder |
| Uses | Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin. |
| Definition | ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall as the monohydrochloride salt) for the treatment of bacterial infections in dogs. |
Difloxacin Preparation Products And Raw materials
