Introduction：Basic information about Diphenhydramine citrate CAS 88637-37-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Diphenhydramine citrate Basic information
| Product Name: | Diphenhydramine citrate |
| Synonyms: | [2-(diphenylmethoxy)ethyl]dimethylammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate;Diphenhydramine Citrate (125 mg);Diphenhydramine Citrate (200 mg);2-(benzhydryloxy)-N,N-diMethylethanaMine 2-hydroxypropane-1,2,3-tricarboxylate;Benzhydramine citrate;DIPHENHYDRAMINE CITRATE;Diphenhydramine citrate USP/EP/BP;2-benzhydryloxy-N,N-dimethylethanamine,2-hydroxypropane-1,2,3-tricarboxylic acid |
| CAS: | 88637-37-0 |
| MF: | C23H29NO8 |
| MW: | 447.48 |
| EINECS: | 289-432-0 |
| Product Categories: | |
| Mol File: | 88637-37-0.mol |
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Diphenhydramine citrate Chemical Properties
| Melting point | 148-150°C |
| storage temp. | Room Temperature |
| solubility | DMSO, Methanol |
| form | Solid |
| color | White |
| Major Application | pharmaceutical |
| InChIKey | SPCKHVPPRJWQRZ-UHFFFAOYSA-N |
| SMILES | N(CCOC(c2ccccc2)c1ccccc1)(C)C.OC(CC(=O)O)(CC(=O)O)C(=O)O |
Safety Information
| WGK Germany | 3 |
| HS Code | 2922190900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2 |
Diphenhydramine citrate Usage And Synthesis
| Uses | Antihistaminic. |
| Uses | Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic. |
| Synthesis | Benzylhydramine hydrochloride is produced by reacting benzylhydramine hydrochloride with sodium hydroxide, and then benzylhydramine citrate is produced by reacting benzylhydramine citrate with citric acid. However, this method uses benzylamine hydrochloride as the starting material and is costly. |
Diphenhydramine citrate Preparation Products And Raw materials
