Introduction：Basic information about Dipivefrin hydrochloride CAS 64019-93-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dipivefrin hydrochloride Basic information
| Product Name: | Dipivefrin hydrochloride |
| Synonyms: | dipivalylepinephrinehydrochloride;dipivefrinehydrochloride;dipivefrinhydrochloride;hydrochloride,(+-)-este;propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene;Progate;Propanoic acid,2,2-diMethyl-, 1,1'-[4-[1-hydroxy-2-(MethylaMino)ethyl]-1,2-phenylene] ester,hydrochloride (1:1);DIPIVEFRIN HYDROCHLORIDE (200 MG) |
| CAS: | 64019-93-8 |
| MF: | C19H30ClNO5 |
| MW: | 387.8982 |
| EINECS: | 264-609-5 |
| Product Categories: | API |
| Mol File: | 64019-93-8.mol |
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Dipivefrin hydrochloride Chemical Properties
| Melting point | 158-159° |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride. |
| form | Solid |
| pka | 8.40(at 25℃) |
| color | White to Off-White |
| Major Application | pharmaceutical (small molecule) |
| InChI | InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H |
| InChIKey | VKFAUCPBMAGVRG-UHFFFAOYSA-N |
| SMILES | C1(OC(=O)C(C)(C)C)=CC(=CC=C1OC(=O)C(C)(C)C)C(O)CNC.Cl |
Safety Information
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| HS Code | 2922504500 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
Dipivefrin hydrochloride Usage And Synthesis
| Description | Dipivefrin hydrochloride is an antiglaucoma prothrombotic drug that is hydrolyzed to its active compound epinephrine by esterases in the cornea. |
| Chemical Properties | White or almost white, crystalline powder. |
| Uses | Dipivefrine Hydrochloride acts as an anti-glaucoma agent. |
| Uses | Adrenergic (ophthalmic) |
| Definition | ChEBI: The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. |
| Brand name | Akpro (Akorn); Propine (Allergan). |
| in vivo | Dipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms. |
Dipivefrin hydrochloride Preparation Products And Raw materials
