Introduction：Basic information about DL-Histidine CAS 4998-57-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DL-Histidine Basic information
| Product Name: | DL-Histidine |
| Synonyms: | 1H-Imidazole-4-alanine;D-Histidine/L-histidine,(1:1);rac-(R*)-2-Amino-3-(4-imidazolyl)propionic acid;DL-Histidine,98%;DL-Histdine;H-DL-His-OH (DL-Histidine;DL-Histidine 0;DL-Histidine |
| CAS: | 4998-57-6 |
| MF: | C6H9N3O2 |
| MW: | 155.15 |
| EINECS: | 225-660-9 |
| Product Categories: | alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids |
| Mol File: | 4998-57-6.mol |
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DL-Histidine Chemical Properties
| Melting point | 273 °C (dec.)(lit.) |
| Boiling point | 278.95°C (rough estimate) |
| density | 1.3092 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 0.5 M HCl: soluble |
| pka | 1.8(at 25℃) |
| form | powder to crystal |
| color | White to Almost white |
| Merck | 14,4720 |
| BRN | 7800 |
| Major Application | peptide synthesis |
| Cosmetic Ingredient Review (CIR) | DL-Histidine (4998-57-6) |
| InChI | 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11) |
| InChIKey | HNDVDQJCIGZPNO-UHFFFAOYSA-N |
| SMILES | NC(Cc1c[nH]cn1)C(O)=O |
| CAS DataBase Reference | 4998-57-6(CAS DataBase Reference) |
| EPA Substance Registry System | Histidine (4998-57-6) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-36/37-26 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
DL-Histidine Usage And Synthesis
| Chemical Properties | white to slightly yellow crystalline powder |
| Uses | histidine is a skin-conditioning amino acid. |
| Uses | DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone). |
| Definition | ChEBI: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. |
| Synthesis Reference(s) | Journal of the American Chemical Society, 67, p. 502, 1945 DOI: 10.1021/ja01219a513
Chemical and Pharmaceutical Bulletin, 35, p. 3447, 1987 |
| Biochem/physiol Actions | L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine. |
DL-Histidine Preparation Products And Raw materials
| Raw materials | Erythromycin Estolate-->Histamine |
| Preparation Products | ALLYLUREA |
