FENCHLORPHOS CAS 299-84-3
Introduction：Basic information about FENCHLORPHOS CAS 299-84-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
FENCHLORPHOS Basic information
| Product Name: | FENCHLORPHOS |
| Synonyms: | KORLAN(R);ETROLENE;FENCHLORPHOS;DOW ET-14;NANKOR(R);RONNEL;RONNEL(R);O,O-DIMETHYL O-(2,4,5-TRICHLOROPHENYL) PHOSPHOROTHIATE |
| CAS: | 299-84-3 |
| MF: | C8H8Cl3O3PS |
| MW: | 321.55 |
| EINECS: | 206-082-6 |
| Product Categories: | E-GAlphabetic;F;FA - FLPesticides;Insecticides;Organophorous;Pesticides&Metabolites;Alpha sort |
| Mol File: | 299-84-3.mol |
FENCHLORPHOS Chemical Properties
| Melting point | 41.0℃ |
| Boiling point | 97℃ |
| density | 1.485 g/cm3 (25 ºC) |
| vapor pressure | 5.29 at 20 °C, 18.6 at 30 °C (Freed et al., 1977) |
| refractive index | 1.5585 (589.3 nm 20℃) |
| Fp | -18 °C |
| storage temp. | APPROX 4°C |
| solubility | Soluble in acetone, carbon tetrachloride, ether, kerosene, methylene chloride, and toluene(Windholz et al., 1983) |
| form | solid |
| color | White to light brown, waxy solid |
| Water Solubility | 40mg/L(room temperature) |
| Merck | 13,8337 |
| BRN | 1885571 |
| Henry's Law Constant | 8.46 at 25 °C (approximate - calculated from water solubility and vapor pressure) |
| Exposure limits | NIOSH REL: TWA 10 mg/m3, IDLH 300 mg/m3; OSHA PEL: TWA15 mg/m3; ACGIH TLV: TWA 10 mg/m3. |
| Major Application | agriculture environmental |
| InChI | 1S/C8H8Cl3O3PS/c1-12-15(16,13-2)14-8-4-6(10)5(9)3-7(8)11/h3-4H,1-2H3 |
| InChIKey | JHJOOSLFWRRSGU-UHFFFAOYSA-N |
| SMILES | COP(=S)(OC)Oc1cc(Cl)c(Cl)cc1Cl |
| EPA Substance Registry System | Ronnel (299-84-3) |
Safety Information
| Hazard Codes | Xn,N,F |
| Risk Statements | 21/22-50/53-67-65-38-11 |
| Safety Statements | 25-36/37-60-61-62 |
| RIDADR | UN 1145 3/PG 2 |
| OEB | B |
| OEL | TWA: 10 mg/m3 |
| WGK Germany | 3 |
| RTECS | TG0525000 |
| HS Code | 29201900 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
| Hazardous Substances Data | 299-84-3(Hazardous Substances Data) |
| Toxicity | LD50 in male, female rats (mg/kg): 1250, 2630 orally (Gaines) |
| IDLA | 300 mg/m3 |
| Description | Ronnel is a white to light tan crystalline solid.Molecular weight =321.54; Specific gravity (H2O:1) =1.48 at 25℃; Boiling point =(decomposes); Freezing/Melting point= 41℃. Practically insoluble in water;solubility = 0.004% at 25℃. |
| Chemical Properties | Powder or granules. Insolublein water; soluble in most organic solvents. |
| Chemical Properties | Ronnel is a white to light tan crystallinesolid. |
| Uses | Systemic insecticide in livestock |
| Uses | Insecticide. |
| Definition | ChEBI: Fenchlorphos is an organic thiophosphate. |
| General Description | White to light-tan crystalline solid. Mp: 41° C, Density :1.49 g cm-3 at 25°C. Biocidal (toxic to all animal life in differing degrees) by its action as a cholinesterase inhibitor. Used as an insecticide. Degrades readily in the environment by hydrolysis and oxidation. |
| Reactivity Profile | FENCHLORPHOS is non-flammable and non-combustible. Decomposes with heating to evolve toxic and corrosive vapors (hydrogen chloride, phosphorus oxides, sulfur oxides). Incompatible with strong oxidizing agents. |
| Hazard | Toxic by ingestion and inhalation.Cholinesterase inhibitor, use may be restricted.Questionable carcinogen. |
| Health Hazard | Ronnel is a weak cholinesteraseinhibitor and has low toxicity.On both single and repeated doses, ronnelaffects the pseudoesterase of the plasma ratherthan the true acetylcholinesterase of the redblood cells.Ronnel has not been shown to potentiatethe effect of other commonly used organophosphorusinsecticides. |
| Safety Profile | Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. A cholinesterase inhibitor. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Cl-, POx, and SOx. See also PARATHION and CHLOROPHENOLS. |
| Potential Exposure | Ronnel is both an organochlorine andorganophosphorus compound; potential danger to thoseinvolved in manufacture, formulation and application of thisinsecticide for farm (livestock) and household uses. Degradesreadily in the environment by hydrolysis and oxidation . |
| First aid | If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, beginrescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. |
| Environmental Fate | Chemical/Physical. Though no products were identified, the reported hydrolysis halflife at pH 7.4 and 70°C using a 1:4 ethanol/water mixture is 10.2–10.4 hours (Freed etal., 1977). Ronnel decomposed at elevated temperatures on five clay surfaces, each treatedwith hydrogen, calcium, magnesium, aluminum and iron ions. At temperatures <950°C(125, 300 and 750°C), bentonite clays impregnated with technical ronnel (18.6 wt %)decomposed to 2,4,5-trichlorophenol and a rearrangement product tentatively identifiedas O-methyl S-methyl-O-(2,4,5-trichlorophenyl) phosphorothioate (Rosenfield and VanValkenburg, 1965). At 950°C, only the latter product formed. It was postulated that thiscompound resulted from an acid-catalyzed molecular rearrangement reaction. Ronnel alsoundergoes base-catalyzed hydrolysis at elevated temperatures. Products include methanoland a new compound that is formed via cleavage of a methyl group from one of themethoxy groups, which is then bonded to the sulfur atom (Rosenfield and Van Valkenburg,1965). Ronnel is stable to hydrolysis over the pH range of 5–6 (Mortland and Raman, 1967).However, in the presence of a Cu(II) salt (as cupric chloride) or when present as theexchangeable Cu(II) cation in montmorillonite clays, ronnel is completely hydrolyzed viafirst-order kinetics in <24 hours at 20°C. The calculated half-life of ronnel at 20°C forthis reaction is 6.0 hours. It was suggested that decomposition in the presence of Cu(II)was a result of coordination of the copper atom through the oxygen or sulfur on thephosphorus atom resulting in the cleavage of the side chain containing the phosphorus atom forming O,O-ethyl-O-phosphorothioate and 1,2,4-trichlorobenzene (Mortland andRaman, 1967). Emits very toxic fumes of chlorides, sulfur and phosphorus oxides when heated todecomposition (Lewis, 1990). |
| storage | Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from strong oxidizers. Where possible,automatically transfer material from drums or other storagecontainers to process containers. Sources of ignition, suchas smoking and open flames, are prohibited where thischemical is handled, used, or stored. Metal containersinvolving the transfer of this chemical should be groundedand bonded. Wherever this chemical is used, handled, manufactured, or stored, use explosion-proof electrical equipment and fittings. |
| Shipping | UN2811 Toxic solids, organic, n.o.s., HazardClass: 6.1; Labels: 6.1-Poisonous materials, Technical NameRequired. UN2783 Organophosphorus pesticides, solid, toxic,Hazard Class: 6.1; Labels: 6.1-Poisonous materials. |
| Incompatibilities | Incompatible with oxidizers (chlorates,nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explo-sions. Keep away from alkaline materials, strong bases,strong acids, oxoacids, and epoxides. Store at temperatures＜25-30℃. Organothiophosphates are susceptible toformation of highly toxic and flammable phosphine gas inthe presence of strong reducing agents such as hydridedsand active metals. Partial oxidation by oxidizing agentsmay result in the release of toxic phosphorus oxides |
| Waste Disposal | Incineration with added flam-mable solvent in furnace equipped with afterburner andalkali scrubber . In accordance with 40CFR165, followrecommendations for the disposal of pesticides and pesti-cide containers. Must be disposed properly by followingpackage label directions or by contacting your local or fed-eral environmental control agency, or by contacting yourregional EPA office. |
FENCHLORPHOS Preparation Products And Raw materials
| Raw materials | 2,4,5-Trichlorophenol-->o-(2,4,5-trichlorophenyl) phosphorodichloridothioate-->Parathion-methyl-->DICAPTHON-->Dimethyl chlorothiophosphate-->Fenitrothion |
| Preparation Products | FENCHLORPHOS-OXON |
