Grela 2nd Generation CAS 502964-52-5

Introduction：Basic information about Grela 2nd Generation CAS 502964-52-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Grela 2nd Generation Basic information

• Product Name: Grela 2nd Generation
• Synonyms: RutheniuM, [1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro[[2-(1-Methylethoxy-κO)-5-nitrophenyl]Methylene-κC]-, (SP-5-41)-;[1,3-bis (2,4,6-trimethylphenyl) -2- imidazolidinylidene] (2-isopropoxy-5-nitrophenyl methylene) ruthenium dichloride;nitro-Grela;(SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-kO)-5-nitrophenyl]Methylene-kC]-ruthenium;Grela nitro-Grela;1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(5-nitro-2-propan-2-yloxyphenyl)methylidene]ruthenium;Grela's catalyst;Grela 2
• CAS: 502964-52-5
• MF: C31H36Cl2N3O3Ru
• MW: 670.62
• Mol File: 502964-52-5.mol

Grela 2nd Generation Chemical Properties

• Melting point: >300 °C
• storage temp.: 2-8°C
• form: Powder
• color: green
• InChIKey: WJQJERDWEICOQD-UHFFFAOYSA-L
• SMILES: [Cl-][Ru+6]1(=[C-2]2N(C3C(=CC(C)=CC=3C)C)CCN2C2C(=CC(C)=CC=2C)C)(=[C-2]C2=CC(N(=O)=O)=CC=C2O1C(C)C)[Cl-]
• CAS DataBase Reference: 502964-52-5

Safety Information

• WGK Germany: WGK 3
• HS Code: 2931.90.6000
• Storage Class: 11 - Combustible Solids

Grela 2nd Generation Usage And Synthesis

Reaction

1. This catalyst is used for an efficient synthesis of HCV Protease Inhibitor, BILN 2061.
2. The nitro-Grela catalyst is a stable olefin metathesis initiator active in various ring-closing, cross, and enyne metathesis reactions. Its efficiency has been proven in numerous total syntheses of natural and biologically active compounds, and in material science.

Uses

nitro-Grela is a universal catalyst which provides good results in a wide spectrum of olefin metathesis transformations. The catalyst provides high efficiency in cross metathesis (CM) reactions between type 1 olefins and an electron deficient partner. The catalyst is very good for CM of disubstituted internal olefins.

reaction suitability

core: ruthenium
reagent type: catalyst