Introduction：Basic information about heparinase I CAS 9025-39-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
heparinase I Basic information
| Product Name: | heparinase I |
| Synonyms: | HEPARIN LYASE I;HEPARINASE;HEPARINASE I;EC 4.2.2.7;Neutralase;Lyase, heparin;Heparin lyaseI, Heparinase;HeparinaseI from Flavobacterium heparinum,Heparin lyaseI, Heparinase |
| CAS: | 9025-39-2 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | |
| Product Categories: | |
| Mol File: | Mol File |
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heparinase I Chemical Properties
| storage temp. | -20°C |
| form | lyophilized solid |
| color | White to off-white |
| Specific Activity | ≥200units/mg protein (enzyme + BSA) |
| Major Application | diagnostic assay manufacturing |
Safety Information
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Resp. Sens. 1 |
heparinase I Usage And Synthesis
| Uses | Heparinase I from Flavobacterium heparinum has been used:
- in the digestion of plasma samples
- to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
- in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells
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| Biochem/physiol Actions | Heparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes. |
heparinase I Preparation Products And Raw materials
