HOMATROPINE HYDROCHLORIDE CAS 637-21-8

Introduction：Basic information about HOMATROPINE HYDROCHLORIDE CAS 637-21-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

HOMATROPINE HYDROCHLORIDE Basic information

• Product Name: HOMATROPINE HYDROCHLORIDE
• Synonyms: HOMATROPINE HYDROCHLORIDE;homatropineHCl;Homatropinhydrochlorid;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate hydrochloride;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenyl-ethanoate hydrochloride;2-hydroxy-2-phenyl-acetic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride;HomatropineHydrochloride>(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]Octan-3-yl 2-hydroxy-2-phenylacetate hydrochloride
• CAS: 637-21-8
• MF: C16H22ClNO3
• MW: 311.8
• EINECS: 211-280-0
• Product Categories: Biochemistry;Tropane Alkaloids;Alkaloids
• Mol File: 637-21-8.mol

HOMATROPINE HYDROCHLORIDE Chemical Properties

• Melting point: 226 °C
• storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• solubility: Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly)
• form: Solid
• color: White to Off-White
• Merck: 14,4730
• InChI: InChI=1S/C4H3ClF4O2/c1-11-2(10)3(6,7)4(5,8)9/h1H3
• InChIKey: FRMDDIJBLQNNTC-RDYJJYPNSA-N
• SMILES: Cl.N1([C@@H]2C[C@H](C[C@H]1CC2)OC(=O)C(O)c3ccccc3)C
• CAS DataBase Reference: 637-21-8

Safety Information

• RIDADR: UN 1544 6.1/PG III
• WGK Germany: WGK 3
• HS Code: 2939.79.0000
• HazardClass: 6.1
• PackingGroup: III
• Storage Class: 11 - Combustible Solids

HOMATROPINE HYDROCHLORIDE Usage And Synthesis

Uses

Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1].

References

[1] Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126(2):515-24. DOI:10.1093/toxsci/kfs009