horminone CAS 21887-01-4

Introduction：Basic information about horminone CAS 21887-01-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

horminone Basic information

• Product Name: horminone
• Synonyms: horminone;7ALPHA,12-DIHYDROXY-8,12-ABIETADIENE-11,14-DIONE;(4bS)-1,4,4b,5,6,7,8,8aβ,9,10-Decahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione;(4bS)-4b,5,6,7,8,8aβ,9,10-Octahydro-3,10β-dihydroxy-2-isopropyl-4bα,8,8-trimethyl-1,4-phenanthrenedione;7α,12-Dihydroxyabieta-8,12-diene-11,14-dione;7α-Hydroxyroyleanone;1,4-Phenanthrenedione, 4B,5,6,7,8,8A,9,10-octahydro-3,10-dihydroxy-4B,8,8-trimethyl-2-(1-methylethyl)-;Aids031165
• CAS: 21887-01-4
• MF: C20H28O4
• MW: 332.43
• Mol File: 21887-01-4.mol

horminone Chemical Properties

• Melting point: 178 °C
• Boiling point: 469.3±45.0 °C(Predicted)
• density: 1.19±0.1 g/cm3(Predicted)
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: powder
• pka: 4.50±1.00(Predicted)
• color: Yellow

horminone Usage And Synthesis

Uses

Horminone is an abietan diterpene quinone that can be isolated from Labiatae family. Horminone increases of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels in vivo. Horminone inhibits the growth of Trypanosoma cruzi and shows antibacterial activity[1].

Definition

ChEBI: An abietane diterpenoid that is abieta-8,12-diene substituted by hydroxy groups at positions 7 and 12 and oxo groups at positions 11 and 14 (the 7alpha stereoisomer) .

target

DNA/RNA Synthesis | NADPH-oxidase | Antifection

References

[1] Inés Nicolás, et al. Theoretical study of the structure and antimicrobial activity of horminone. Theoretical Biochemistry and Biophysics. 2003.