Introduction：Basic information about ISOSAKURANETIN CAS 480-43-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
ISOSAKURANETIN Basic information
| Product Name: | ISOSAKURANETIN |
| Synonyms: | 5,7-DIHYDROXY-4'-METHOXYFLAVANONE;ISOSAKURANETIN;(S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone;ISOSAKURANETIN(P);5,7-DIHYDROXY-4''-METHOXYFLAVANONE hplc;ISOSAKURANETIN WITH HPLC;(2S)-5,7-Dihydroxy-4'-methoxyflavanone;(S)-2,3-Dihydro-2-(4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| CAS: | 480-43-3 |
| MF: | C16H14O5 |
| MW: | 286.28 |
| EINECS: | 207-551-8 |
| Product Categories: | Flavanones;Flavonoids |
| Mol File: | 480-43-3.mol |
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ISOSAKURANETIN Chemical Properties
| Melting point | 193-194°C |
| Boiling point | 539.2±50.0 °C(Predicted) |
| density | 1.370±0.06 g/cm3(Predicted) |
| solubility | DMSO : 125 mg/mL (436.64 mM; Need ultrasonic and warming) |
| form | powder |
| pka | 7.50±0.40(Predicted) |
| color | White |
| LogP | 3.840 (est) |
Safety Information
| Risk Statements | 22 |
| Safety Statements | 22-45 |
| HS Code | 29329990 |
ISOSAKURANETIN Usage And Synthesis
| Chemical Properties | Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It comes from Prunus serrulata, a plant of the genus Prunus in the Rosaceae family. |
| Uses | (S)-Isosakuranetin, is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. |
| Definition | ChEBI: A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 4' (the 2S stereoisomer). |
| in vivo | Isosakuranetin dose-dependently increases the paw-withdrawal threshold within the dose range of 1.5 to 6 mg/kg. Post hoc analysis reveals that Isosakuranetin increases the paw-withdrawal threshold and statistical significance is seen at times 30 and 40 min for the dose of 3 mg/kg and 30 to 60 min for the dose of 6 mg/kg[2]. |
| target | ERK | PI3K | Akt | JNK | PKA | GSK-3 | Calcium Channel | Potassium Channel | Tyrosinase | TRPM3 | TRP1 | TRP2 |
ISOSAKURANETIN Preparation Products And Raw materials
