Introduction:Basic information about L-Cysteine hydrochloride monohydrate CAS 7048-04-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
L-Cysteine hydrochloride monohydrate Basic informationApplication General descriptio
| Product Name: | L-Cysteine hydrochloride monohydrate |
| Synonyms: | (R)-(+)-CYSTEINE HYDROCHLORIDE HYDRATE;H-L-CYS-OH HCL H2O;H-CYS-OH HCL H2O;CYSTEINI HYDROCHLORIDUM MONOHYDRICUM;CYSTEINE HYDROCHLORIDE MONOHYDRATE;CYSTEINE HCL H2O;3-MERCAPTO-2-AMINOPROPIONIC ACID HYDROCHLORIDE;3-MERCAPTO-2-AMINOPROPIONIC ACID HYDROCHLORIDE MONOHYDRATE |
| CAS: | 7048-04-6 |
| MF: | C3H10ClNO3S |
| MW: | 175.63 |
| EINECS: | 615-117-8 |
| Product Categories: | Amino acid;amino;Cysteine [Cys, C];alpha-Amino Acids;Amino Acids;Antioxidant;Biochemistry;BioUltra;Cysteine/CystineIon Channels;Excitatory Amino Acids;Ionotropic Glutamate Receptor ModulatorsNeurotransmitters;Ligand-Gated Ion Channels;NMDA Agonists;Nutritional Supplements;L-Amino Acids;Amino AcidsPharmacopoeia (USP);Pharmacopoeia A-ZPharmacopoeia (USP);Pharmacopoeial Amino Acids;Amino Acids;Biochemicals and Reagents;Amino AcidsBiochemicals and Reagents;Core Bioreagents;Research Essentials;Amino AcidsPeptide Synthesis;Amino Acid Derivatives;Cysteine/Cystine |
| Mol File: | 7048-04-6.mol |
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L-Cysteine hydrochloride monohydrate Chemical Properties
| Melting point | 175°C |
| alpha | +6.0~+7.5゜ (20℃/D)(c=8,6mol/l HCl)(calculated on the dried basis) |
| bulk density | 780kg/m3 |
| density | 1.54 g/cm3 |
| vapor pressure | <0.1 hPa (20 °C) |
| refractive index | 6 ° (C=8, 1mol/L HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Solid |
| color | White |
| PH | 0.8-1.2 (100g/l, H2O, 20℃) |
| PH Range | 1 - 2 |
| Optical Rotation | [α]20/D +5.6±0.3°, c = 5% in 5 M HCl |
| biological source | synthetic |
| Water Solubility | Soluble in cold water. |
| λmax | λ: 260 nm Amax: 1.0 λ: 280 nm Amax: 0.3 |
| Sensitive | Hygroscopic |
| Merck | 14,2781 |
| BRN | 5158059 |
| Stability: | Stable. Incompatible with strong oxidizing agents, most common metals, hydrogen chloride. |
| InChI | 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1 |
| InChIKey | QIJRTFXNRTXDIP-JIZZDEOASA-N |
| SMILES | O.Cl.N[C@@H](CS)C(O)=O |
| LogP | 0.235 (est) |
| CAS DataBase Reference | 7048-04-6(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | HA2285000 |
| F | 3-10-23 |
| TSCA | Yes |
| HS Code | 29309013 |
| Storage Class | 11 - Combustible Solids |
L-Cysteine hydrochloride monohydrate Usage And Synthesis
| Application | L-cysteine hydrochloride monohydrate has been used in protocols to isolate dorsal root ganglion neurons (DRG). It was also used in research to test its effect as an inhibitor of enzymatic browning of apples. |
| General descriptio | L-cysteine hydrochloride monohydrate (LCHCMH) is a water-soluble salt of the non-essential amino acid L-cysteine. It is widely used in the pharmaceutical industry. The thermodynamic characteristics of LCHCMH in aqueous solution have been reported. [1] It can be crystallized in an orthogonal system with the P212121 space group. Its nonlinear optical (NLO) characteristics have been studied in single crystals grown by unidirectional Sankaranarayanan-Ramasamy (SR) technology. |
| Chemical Properties | white crystalline powder
|
| Uses | L-Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. L-Cysteine is commonly used as a precursor in the food and pharmaceutical industries. L-Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours. |
| Uses | L-Cysteine hydrochloride monohydrate is used as a precursor in food, pharmaceutical and personal care products. It is actively involved in the production of flavors such as meat flavor obtained by reacting with sugars. It plays an important role as a key raw material for the manufacture of N-acetyl-L-cysteine, S-carboxymethyl-L-cysteine and L-cysteine base. It is involved in the treatment of liver disease as an antioxidant and antidote. Being an essential amino acid, it used as animal feed especially for sheep, which is responsible the growth of wool. |
| Uses | L-Cysteine hydrochloride monohydrate has been used as a component of yeast dropout media for culturing yeasts. It has also been used as a component of differential reinforced clostridial broth (DRCM) for the isolation of clostridia. |
| Definition | ChEBI: A hydrate that is the monohydrate form of L-cysteine hydrochloride. |
| General Description | This product is supplied from Wacker FERMOPURE? material, but is sold for R&D use only, not for drug, household or other uses. |
| reaction suitability | reaction type: solution phase peptide synthesis |
| Biochem/physiol Actions | NMDA glutamatergic receptor antagonist. |
| Purification Methods | Likely impurities are cystine and tyrosine. Crystallise the salt from MeOH by adding diethyl ether, or from hot 20% HCl. Dry it under vacuum over P2O5. Hygroscopic. [Beilstein 4 III 1580, 1600.] |
L-Cysteine hydrochloride monohydrate Preparation Products And Raw materials
| Raw materials | Hydrogen Sulfide-->L-Cystine-->L-Cysteine-->Tin granular |
| Preparation Products | N10-(TRIFLUOROACETYL)PTEROIC ACID-->(2,4-DIAMINOPTERIDIN-6-YL)METHANOL HYDROCHLORIDE HYDRATE-->Phenol Red |