LDAO CAS 1643-20-5
Introduction：Basic information about LDAO CAS 1643-20-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
LDAO Basic information
| Product Name: | LDAO |
| Synonyms: | oxydededimethyllaurylamine;refan;Dodecycldimethylamine oxide;DDAO, Lauryldimethylamine N-oxide, LDAO;LADO;n-Dodeycl-N,N-dimethylamine-N-oxide;N,N-dimethyldodecan-1-amine oxide;Barlox(R) 1260 |
| CAS: | 1643-20-5 |
| MF: | C14H31NO |
| MW: | 229.4 |
| EINECS: | 216-700-6 |
| Product Categories: | Surfactant;Hair Care;Home Care;bc0001;1643-20-5;Glycon Biochem |
| Mol File: | 1643-20-5.mol |
LDAO Chemical Properties
| Melting point | 132-133 °C(lit.) |
| Boiling point | 371.32°C (rough estimate) |
| density | 0.996 g/mL at 20 °C |
| vapor pressure | 0Pa at 25℃ |
| refractive index | n |
| Fp | 113°C (closed cup)(235 |
| storage temp. | -20°C |
| solubility | Ethanol:15.0(Max Conc. mg/mL);65.38(Max Conc. mM) DMF:3.0(Max Conc. mg/mL);1.31(Max Conc. mM) DMSO:0.1(Max Conc. mg/mL);0.44(Max Conc. mM) PBS (pH 7.2):0.1(Max Conc. mg/mL);0.44(Max Conc. mM) |
| pka | 4.79±0.40(Predicted) |
| form | A crystalline solid |
| color | White to off-white |
| Specific Gravity | 0.97 |
| PH | 7.0-9.0 (25°C, 0.1M in H2O) |
| Water Solubility | Insoluble in water. |
| Sensitive | Hygroscopic |
| BRN | 1769927 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Cosmetics Ingredients Functions | CLEANSING SURFACTANT - CLEANSING PERFUMING HAIR CONDITIONING ANTISTATIC SURFACTANT - FOAM BOOSTING SURFACTANT - HYDROTROPE VISCOSITY CONTROLLING |
| Cosmetic Ingredient Review (CIR) | LDAO (1643-20-5) |
| InChI | 1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3 |
| InChIKey | SYELZBGXAIXKHU-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCC[N+](C)([O-])C |
| LogP | 1.85 at 20℃ |
| EPA Substance Registry System | Lauryldimethylamine oxide (1643-20-5) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 34-52/53 |
| Safety Statements | 26-36/37/39-45-27 |
| RIDADR | UN 3259 8/PG 2 |
| WGK Germany | 2 |
| RTECS | JR6650000 |
| F | 3-10 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29299090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 2 Eye Dam. 1 Skin Irrit. 2 |
| Hazardous Substances Data | 1643-20-5(Hazardous Substances Data) |
| Toxicity | mouse,LD50,intraperitoneal,375mg/kg (375mg/kg),French Medicament Patent Document. Vol. #4264M, |
| Description | DDAO is a far-red fluorogenic substrate for esterase and lipase. |
| Chemical Properties | Clear yellow Liquid |
| Uses | Barlox(R) 1260 is a concentrated cocoamine oxide surfactant. Barlox(R) 1260 can be used in a broad number of industriual cleaning applications where coupling, high foaming, detergency and compatibility are important. Product Data Sheet |
| Uses | LDAO is suitable to use in crystallization of membrane proteins. It is also suitable to enhance the detection of high molecular weight proteins. |
| Definition | ChEBI: Dodecyldimethylamine N-oxide is a tertiary amine oxide resulting from the formal oxidation of the amino group of dodecyldimethylamine. It has a role as a plant metabolite and a detergent. It derives from a hydride of a dodecane. |
| Application | Lauryldimethylamine oxide(LDAO) is mainly used in cosmetic and personal care product formulations, particularly in hair care products as a foaming agent, fragrance ingredient, viscosity builder, stabiliser, conditioner, emulsifier, wetting agent and antistatic agent. It is also a biochemical reagent and can be used as a biological material or organic compound for life science related research. |
| General Description | Crystalline solid. |
| Air & Water Reactions | Hygroscopic . |
| Reactivity Profile | LDAO is less basic than the tertiary amine from which LDAO is derived, but still reacts with strong acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Fire Hazard | Flash point data for LDAO are not available. LDAO is probably nonflammable. |
| Flammability and Explosibility | Not classified |
| Biochem/physiol Actions | LDAO can be used to disrupt phospholipid bilayer of cells. |
| Purification Methods | Crystallise the oxide from acetone or ethyl acetate. [Bunton et al. J Org Chem 52 3832 1987, Beilstein 4 III 410, 4 IV 798.] |
| Excitation / Emission Maximum | 646 nm/659 nm |
LDAO Preparation Products And Raw materials
| Raw materials | Hydrogen peroxide-->Dodecylamine |
