Introduction：Basic information about LOSARTAN-D4 CAS 1030937-27-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
LOSARTAN-D4 Basic information
| Product Name: | LOSARTAN-D4 |
| Synonyms: | Reaxys ID: 18951469;2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5yl)[1,1'-biphenyl-d4]-4-yl]Methyl]-1H-iMidazole-5-Methanol;Cozaar-d4;MK-954-d4;LOSARTAN-D4;2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl-2,3,5,6-d4]methyl]-1H-imidazole-5-methanol;[2H4]-Losartan;DuP-753 D4 |
| CAS: | 1030937-27-9 |
| MF: | C22H19ClD4N6O |
| MW: | 426.94 |
| EINECS: | |
| Product Categories: | Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals |
| Mol File: | Mol File |
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LOSARTAN-D4 Chemical Properties
| Melting point | 184-190?C |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly),Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
Safety Information
LOSARTAN-D4 Usage And Synthesis
| Description | Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM. |
| Chemical Properties | White Solid |
| Uses | Losartan-d4 can be intended for use as an internal standard for the quantification of Losartan by GC- or LC-mass spectrometry. |
| Uses | A labelled version of Losartan, a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. |
| Uses | As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive. |
| IC 50 | AT1 Receptor |
LOSARTAN-D4 Preparation Products And Raw materials
