Introduction：Basic information about mersalyl CAS 492-18-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
mersalyl Basic information
| Product Name: | mersalyl |
| Synonyms: | mersalyl;Mersalylum;EINECS 207-637-5;[3-[[2-(Sodiooxycarbonylmethoxy)benzoyl]amino]-2-methoxypropyl]hydroxymercury(II);Diursal;Igrosin;Mercuramide;Mercurital |
| CAS: | 492-18-2 |
| MF: | C13H16HgNO6.Na |
| MW: | 505.85 |
| EINECS: | 2077489 |
| Product Categories: | |
| Mol File: | 492-18-2.mol |
|
mersalyl Chemical Properties
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
| EPA Substance Registry System | Mercurate(1-), [3-[[2-(carboxylatomethoxy)benzoyl-.kappa.O]amino]-2-methoxypropyl-.kappa.C]hydroxy-, sodium (492-18-2) |
Safety Information
| RIDADR | 2025 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Toxicity | LD50 i.v. in mice, rats: 72.6, 17.7 mg/kg (Robbins, Chen) |
mersalyl Usage And Synthesis
| Uses | Mersalyl Acid Sodium Salt is used in biological studies to evaluate its effect on inositol triphosphate receptor binding and ion channel function. |
| Brand name | Salyrgan(Sterling Winthrop). |
| Safety Profile | Poison by intravenous, intramuscular, and intraperitoneal routes. Used as a diuretic agent. When heated to decomposition it emits very toxic fumes of Hg, NOx, and Na2O. See also MERCURY COMPOUNDS. |
| in vivo | Mersalyl (2.5-40 mg/kg; intramuscularly injection) shows diuresis effects in Rats[3]. | Animal Model: | Rats[3] | | Dosage: | 2.5-40 mg/kg | | Administration: | Intramuscularly injection | | Result: | Significantly depressed in sulfhydryl concentration at 5 mg/kg. |
|
mersalyl Preparation Products And Raw materials
