Methylophiopogonanone B CAS 74805-91-7

Introduction：Basic information about Methylophiopogonanone B CAS 74805-91-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Methylophiopogonanone B Basic information

• Product Name: Methylophiopogonanone B
• Synonyms: (3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-4H-1-benzopyran-4-one;Methylophiopogonanone B;NE-IV;R-Methylophiopogonanone B;Methylophiopogonanone B(R-Methylophiopogonanone B);8-Methylophiopogonanone B;3-(4'-methoxy-benzyl)-5,7-dihydroxy-6,8-dimethyl-chroman-4-one;(3R)-5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-one
• CAS: 74805-91-7
• MF: C19H20O5
• MW: 328.36
• Mol File: 74805-91-7.mol

Methylophiopogonanone B Chemical Properties

• Boiling point: 554.5±49.0 °C(Predicted)
• density: 1.285
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Soluble in acetone, chloroform and methanol;
• form: powder
• pka: 8.24±0.40(Predicted)
• color: Light yellow
• Water Solubility: insoluble in water

Methylophiopogonanone B Usage And Synthesis

Description

Methylophiopogonanone B (MO‑B), which belongs to a group of homoisoflavonoids, present in Ophiopogon japonicus, has been identified as an active component with antioxidative and anti‑tumor properties.

Chemical Properties

Methylophiopogonanone B is soluble in methanol, ethanol, DMSO and other organic solvents, and is derived from the fibrous root of Ophiopogon japonicus.

Uses

Methylophiopogonanone B has the effect of enhancing protease activity and regulating cytoskeleton remodeling.

Synthesis

Methylophiopogonanone B was synthesized from 2,4,6-trihydroxy-3,5-dimethylacetophenone in 57% yield.

References

[1] M. FUJII. First synthesis of racemic methylophiopogonanone B and its inhibitory activity of hypoxia-inducible factor-1α[J]. Heterocycles, 2009, 78 1: 207-212. DOI:10.3987/COM-08-11517.