Introduction：Basic information about Naftalofos CAS 1491-41-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Naftalofos Basic information
| Product Name: | Naftalofos |
| Synonyms: | e9002;ent25,567;Phosphoric acid, 1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl diethyl ester;phosphoric acid (1,3-dioxo-2-benzo[de]isoquinolinyl) diethyl ester;Phosphoric acid, N-hydroxynaphthalimide O,O-diethyl ester;maretin;n-hydroxy-naphthalimiddiethylphosphate;n-hydroxynaphthylimidediethylphosphate |
| CAS: | 1491-41-4 |
| MF: | C16H16NO6P |
| MW: | 349.28 |
| EINECS: | 216-078-6 |
| Product Categories: | |
| Mol File: | 1491-41-4.mol |
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Naftalofos Chemical Properties
| Melting point | 174-179° |
| storage temp. | 0-6°C |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| form | solid |
| Boiling point | 487.3±28.0 °C(Predicted) |
| density | 1.41±0.1 g/cm3(Predicted) |
| CAS DataBase Reference | 1491-41-4(CAS DataBase Reference) |
| EPA Substance Registry System | Naftalofos (1491-41-4) |
Safety Information
| Hazard Codes | T |
| Risk Statements | 24/25 |
| Safety Statements | 36/37-45 |
| RIDADR | 2783 |
| WGK Germany | 3 |
| RTECS | QK5775000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | chicken,LD50,oral,43300ug/kg (43.3mg/kg),PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967. |
Naftalofos Usage And Synthesis
| Uses | Anthelmintic(veterinary). |
| Definition | ChEBI: Naftalofos is an organic heterotricyclic compound. It has a role as an anthelminthic drug. |
| Brand name | Maretin (Bayer Animal Health). |
| Synthesis | Naftalofos is synthesised through a multi-step chemical process that begins with the preparation of O-ethyl phenylphosphonothioic acid, which serves as the phosphorus-containing core. This intermediate is then reacted with 2-naphthol, a hydroxylated aromatic compound, via esterification, forming the characteristic O-naphthyl linkage. After the coupling step, the crude product undergoes purification to isolate. |
Naftalofos Preparation Products And Raw materials
