Introduction：Basic information about N-methyl-N'-(azide-PEG3)-Cy3 CAS 2107273-16-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
N-methyl-N'-(azide-PEG3)-Cy3 Basic information
| Product Name: | N-methyl-N'-(azide-PEG3)-Cy3 |
| Synonyms: | N-methyl-N'-(azide-PEG3)-Cy3;N-Methyl-N'-(N3-PEG3-CH2CH2)-Cy3 |
| CAS: | 2107273-16-3 |
| MF: | C32H42ClN5O3 |
| MW: | 580.17 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 2107273-16-3.mol |
|
N-methyl-N'-(azide-PEG3)-Cy3 Chemical Properties
| solubility | Soluble in DMSO, DMF, DCM, low solubility in water |
Safety Information
N-methyl-N'-(azide-PEG3)-Cy3 Usage And Synthesis
| Description | N-methyl-N'-(azide-PEG3)-Cy3 is a PEG linker containing cyanine dye with excitation/emmission maximum 555/570 nm as well as an azide group, which enables Click Chemistry. The hydophilic PEG spacer increases solubility in aqueous media. |
| Uses | N-methyl-N'-(azide-PEG3)-Cy3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-methyl-N'-(azide-PEG3)-Cy3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. |
| IC 50 | PEGs |
| References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
N-methyl-N'-(azide-PEG3)-Cy3 Preparation Products And Raw materials
