PEPTIDE YY, HUMAN CAS 118997-30-1

Introduction：Basic information about PEPTIDE YY, HUMAN CAS 118997-30-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

PEPTIDE YY, HUMAN Basic information

• Product Name: PEPTIDE YY, HUMAN
• Synonyms: H-TYR-PRO-ILE-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-ASN-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2;PEPTIDE YY PYY HUMAN;PEPTIDE TYROSINE TYROSINE, HUMAN;PEPTIDE YY, HUMAN;PYY (HUMAN);TYR-PRO-ILE-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-ASN-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2;YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY-NH2;PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
• CAS: 118997-30-1
• MF: C194H295N55O57
• MW: 4309.7524
• Product Categories: Peptide;Neuropeptide Y (NPY ) receptor
• Mol File: 118997-30-1.mol

PEPTIDE YY, HUMAN Chemical Properties

• storage temp.: −20°C
• form: Solid
• color: White to off-white
• biological source: synthetic
• Water Solubility: 1mg/mL in water
• Sequence: H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
• InChIKey: YNXLOPYTAAFMTN-SBUIBGKBSA-N

Safety Information

• WGK Germany: 3
• Storage Class: 11 - Combustible Solids

PEPTIDE YY, HUMAN Usage And Synthesis

Uses

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

General Description

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

Biochem/physiol Actions

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

in vivo

Peptide YY is capable of strongly inhibiting secretin-stimulated pancreatic secretion. A very low dose of Peptide YY (10-20 pmol/kg) significantly decreases the pancreatic secretion of bicarbonate as well as fluid that is stimulated by a single dose of secretin (0.1 unit/kg). A dose of Peptide YY of 100-200 pmol/kg causes a 70-80% reduction of the pancreatic bicarbonate and fluid secretion^[3]. Peptide YY is localised to blood vessels and atherosclerotic plaques of rabbits. It causes vasoconstriction of the vascular tree^[2].