Poly(ethylene glycol) distearate CAS 9005-08-7
Introduction：Basic information about Poly(ethylene glycol) distearate CAS 9005-08-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Poly(ethylene glycol) distearate Basic information
| Product Name: | Poly(ethylene glycol) distearate |
| Synonyms: | DIETHYLENE GLYCOL DISTEARATE;DGD;Polyethyleneglycol3distearate;polyethyleneglycoldistearate#1000;polyglycoldistearate;s1009;s1013;stabogel |
| CAS: | 9005-08-7 |
| MF: | C19H40O4 |
| MW: | 332.5185 |
| EINECS: | |
| Product Categories: | Cosmetic Ingredients & Chemicals |
| Mol File: | 9005-08-7.mol |
Poly(ethylene glycol) distearate Chemical Properties
| Melting point | 35-37 °C |
| Fp | >230 °F |
| Odor | at 100.00?%. mild waxy |
| Dielectric constant | 2.3（0.0℃） |
| Cosmetics Ingredients Functions | SURFACTANT - EMULSIFYING VISCOSITY CONTROLLING SURFACTANT - CLEANSING CLEANSING |
| Cosmetic Ingredient Review (CIR) | Poly(ethylene glycol) distearate (9005-08-7) |
| InChI | InChI=1S/C17H34O2.C2H6O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19;3-1-2-4/h2-16H2,1H3,(H,18,19);3-4H,1-2H2 |
| InChIKey | QYJQHDWGURXGNL-UHFFFAOYSA-N |
| SMILES | OCCO.CCCCCCCCCCCCCCCCC(O)=O |
| LogP | 5.997 (est) |
| CAS DataBase Reference | 9005-08-7 |
| EPA Substance Registry System | Polyethylene glycol distearate (9005-08-7) |
Safety Information
| WGK Germany | 1 |
| RTECS | TQ4375000 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Chemical Properties | A soft, off-white solid. PH of 10% dispersion 7.26, saponification number variable. Soluble in chlorinated solvents, light esters, and acetone; slightly soluble in alcohols, insoluble in glycols, hydrocarbons, and vegetable oils. Combustible. |
| Uses | Pegosperse(R) 300 DS is used as an emulsifier for personal care and water treatment and as a processing aid in textile industry. |
| Uses | POLY(ETHYLENE GLYCOL) (N) DISTEARATE is used as an emulsifier for personal care and water treatment and as a processing aid in textile industry. |
| Definition | Distearate ester of polyglycol. |
| Production Methods | Polyethylene glycol distearate is prepared by the direct reaction offatty acids, particularly stearic acid, with ethylene oxide. |
| reaction suitability | reagent type: cross-linking reagent reaction type: click chemistry |
| Pharmaceutical Applications | Polyethylene glycol distearate is generally used as emulsifiers in oil-inwater-type creams and lotions. Its hydrophilicity or lipophilicitydepends on the number of ethylene oxide units present: the largerthe number, the greater the hydrophilic properties. Polyoxyl 40stearate has been used as an emulsifying agent in intravenousinfusions. Polyoxyethylene stearates are particularly useful as emulsifyingagents when astringent salts or other strong electrolytes are present.It can also be blended with other surfactants to obtain anyhydrophilic–lipophilic balance for lotions or ointment formulations. |
| Safety Profile | Poison by intravenousroute. When heated to decomposition itemits acrid smoke and irritating fumes. Seealso POLYETHYLENE GLYCOL. |
| Safety | Although Polyethylene glycol distearate is primarily used as emulsifyingagents in topical pharmaceutical formulations, certain materials,particularly polyoxyl 40 stearate, have also been used inintravenous injections and oral preparations. Polyethylene glycol distearate has been tested extensively fortoxicity in animals(8–13) and are widely used in pharmaceutical formulations and cosmetics. It is generally regarded asessentially nontoxic and nonirritant materials. Polyoxyl 8 stearate (hamster, oral): 27 g/kg (rat, oral): 64 g/kg Polyoxyl 20 stearate (mouse, IP): 0.2 g/kg (mouse, IV): 0.87 g/kg |
| storage | Polyoxyethylene stearates are generally stable in the presence of electrolytes and weak acids or bases. Strong acids and bases can cause gradual hydrolysis and saponification. The bulk material should be stored in a well-closed container, in a dry place, at room temperature. |
| Incompatibilities | Polyethylene glycol distearate is unstable in hot alkaline solutionsowing to hydrolysis, and will also saponify with strong acids orbases. Discoloration or precipitation can occur with salicylates,phenolic substances, iodine salts, and salts of bismuth, silver, andtannins.Complex formation with preservatives may alsooccur.The antimicrobial activity of some materials such asbacitracin, chloramphenicol, phenoxymethylpenicillin, sodiumpenicillin, and tetracycline may be reduced in the presence ofpolyoxyethylene stearate concentrations greater than 5% w/w. |
| Regulatory Status | Included in the FDA Inactive Ingredients Database (dentalsolutions; IV injections; ophthalmic preparations; oral capsulesand tablets; otic suspensions; topical creams, emulsions, lotions,ointments, and solutions; and vaginal preparations). Included innonparenteral medicines licensed in the UK. Included in theCanadian List of Acceptable Non-medicinal Ingredients. |
Poly(ethylene glycol) distearate Preparation Products And Raw materials
| Raw materials | Stearic acid |
