Polyoxyethylene lauryl ether CAS 9002-92-0

Introduction:Basic information about Polyoxyethylene lauryl ether CAS 9002-92-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Polyoxyethylene lauryl ether Basic informationDescription Reference

Product Name:Polyoxyethylene lauryl ether
Synonyms:Brij|r L23;BRIJ 35 FOR SYNTHESIS;C12E23;Fatty alcohol polyoxyethylene ether;GENAPOL(R) C-100, DETERGENT;GENAPOL(R) X-080;GENAPOL(R) X-080, DETERGENT;GENAPOL(R) X-100
CAS:9002-92-0
MF:(C2H4O)nC12H26O
MW:1199.55
EINECS:500-002-6
Product Categories:Detergents for Cell Lysis;DetergentsNative Protein Sample Preparation;Cell Lysis and Protein Extraction Reagents;Core Bioreagents;Research Essentials;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Ether Type (Surfactants);Ethylene Glycols & Monofunctional Ethylene Glycols;Functional Materials;Monofunctional Ethylene Glycols;Nonionic Surfactants;Surfactants;9002-92-0
Mol File:9002-92-0.mol

Polyoxyethylene lauryl ether Chemical Properties

Melting point 41-45 °C(lit.)
Boiling point 100 °C(lit.)
density 0.99 g/mL±0.002 g/mL at 20 °C
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.461
Fp >230 °F
storage temp. Store below +30°C.
solubility H2O: 40 mg/mL at 20 °C, clear, colorless
form Waxy Pellets
pka0[at 20 ℃]
color White
OdorOdorless
PH5.5-7.0 (100g/l, H2O, 20℃)
PH Range5.5 - 7.5
biological sourcesynthetic
Water Solubility soluble
FreezingPoint 35.0 to 40.0 ℃
Merck 14,7558
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients FunctionsSURFACTANT - EMULSIFYING
CLEANSING
SURFACTANT - CLEANSING
FRAGRANCE
ANTISTATIC
Cosmetic Ingredient Review (CIR)Polyoxyethylene lauryl ether (9002-92-0)
InChIKeyIEQAICDLOKRSRL-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
LogP2.26 at 25℃
EPA Substance Registry SystemPolyethylene glycol monododecyl ether (9002-92-0)

Safety Information

Hazard Codes Xn,Xi
Risk Statements 22-41-36/37/38-38-37/38-36
Safety Statements 26-39-37/39-36/37/39-36-24/25
RIDADR UN 3082 9/PG 3
WGK Germany 3
RTECS MD0875000
3
TSCA TSCA listed
HS Code 34021300
HS Code 38220000
Storage Class11 - Combustible Solids
Hazardous Substances Data9002-92-0(Hazardous Substances Data)
ToxicityLD50 in mice (mg/kg): 1170 orally, 125 i.v. (Zipf)

Polyoxyethylene lauryl ether Usage And Synthesis

DescriptionAs a non-ionic surfactant, polyoxyethylene lauryl ether has excellent washing, emulsifying, dispersing, wetting, and solubilizing functions. It also shows strong foaming ability, easy rinsing performance, and excellent detergency. Because this substance acts as one of the lowest irritant species among various surfactants, it is often selected as raw material for mild detergents, shampoos (such as baby shampoos), bath lotion, cleansing milk, and cosmetics. In addition, this chemical may function as emulsifier, softener, wetting agent, and foaming agent. In terms of solubilizing function, this product has been demonstrated to assist in solubilization of steroid hormones, benzoic acid derivatives, and barbiturates.1-3 Besides, when used as surfactant emulsifier, polyoxyethylene lauryl ether is proved to be an active agent for preparing nanoemulsions for food applications.4
Reference
  1. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF STEROID-HORMONES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2832-2837.
  2. Tomida, H.; Yotsuyanagi, T.; Ikeda, K., SOLUBILIZATION OF BENZOIC-ACID DERIVATIVES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1978, 26, 2824-2831.
  3. Ikeda, K.; Kato, K.; Tukamoto, T., SOLUBILIZATION OF BARBITURATES BY POLYOXYETHYLENE LAURYL ETHER. Chem. Pharm. Bull. 1971, 19, 2510-+.
  4. Silva, H. D.; Cerqueira, M. A.; Vicente, A. A., Nanoemulsions for Food Applications: Development and Characterization. Food Bioprocess Technol. 2012, 5, 854-867.
Chemical PropertiesWhite or almost white, unctuous and hygroscopic mass, melting at 24 °C into a colourless or yellowish, viscous liquid.
UsesBrij L23 is a a pharmaceutical compound used in the schlerotherapy treatments, in those suffering from blood vessel malformations and mutations.
UsesSolvent; nonionic emulsifier; pharmaceutic aid (surfactant); spermaticide.
UsesEthosperse(R) LA-4 is a medium range HLB, ethoxylated, nonionic ether of lauryl alcohol with broad range pH stability. It is suggested for use as an emulsifier in cosmetics to add body and texture (humectant), in household products and in lubricants.
Production MethodsThe method for producing a Polyoxyethylene Lauryl Ether, which comprises a sulfation step wherein an ethylene oxide addition product of an alkyl alcohol having 8-22 carbon atoms is reacted with an SO3-containing gas, thereby obtaining a sulfated product of the ethylene oxide addition product, and a neutralization step wherein the sulfated product is neutralized, thereby obtaining a sulfate. The ethylene oxide addition product contains from 0.01% by mass to 1% by mass (inclusive) of an alkali metal hydroxide relative to the total mass of the ethylene oxide addition product.
Brand nameBrij 30 (ICI Americas).
General DescriptionClear colorless to light yellow viscous liquid. Colorless at 266°F; brown at 644°F. Bland odor.
Air & Water ReactionsWater soluble.
Reactivity ProfilePolyoxyethylene lauryl ether is incompatible with strong oxidizing agents and strong bases.
Fire HazardPolyoxyethylene lauryl ether is combustible.
Flammability and ExplosibilityNot classified
Biochem/physiol ActionsBrij? L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.
Toxics Screening LevelThe initial threshold screening level (ITSL) for polyoxyethylene lauryl ether is 12 μg/m3 based on an annual averaging time.

Polyoxyethylene lauryl ether Preparation Products And Raw materials

Raw materialsSodium hydroxide-->Hydrogen peroxide-->ETHYLENE OXIDE-->Alkyl alcohol-->Fatty alcohol polyoxyethylene ether N=3-->Storage tank
Preparation ProductsCitral-->Polyacrylonitrile fiber oil-->TERPINEOL-->Spining lubricant agent-->silicone softener RS-->Fluorescent brightener 85-->softener 101-->adhesive 2F of type Dongfeng-->softener VS-->adhesive of type Dongfeng F-->Fluorescent Brightener BC-->binding agent for screen printing-->EA optical plastics-->Fluorescent Brightener 135-->adhesive of type Dongfeng-->Greasing agent,cationic-->brubber latex 202BA-->fluorescent whitening agent JD-3-->Coenzyme Q10-->finishing agent ED for pernyl silk-->rubber latex 109BA-->phthalogen auxiliary BSK-->scouring agent TS-DHC-->dacron oiling agent 73^<#^>-->PHOSPHATIDYLETHANOLAMINE-->adhesive FD-->phthalogen auxiliary agent BSM-->O-Octadecyl-1,2-acetone glycerin acetal-->softener HC-39-->detergent YR-301-->textile oil agent-->Adhesive 707-->Coating paste A-->softener MS-->Phthalocyanine auxiliaries No.1
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