Polypropylene glycol CAS 25322-69-4
Introduction：Basic information about Polypropylene glycol CAS 25322-69-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Polypropylene glycol Basic information
| Product Name: | Polypropylene glycol |
| Synonyms: | POLYPROPYLENE GLYCOL, DIOL TYPE, 1000;POLYPROPYLENE GLYCOL, DIOL TYPE, 2,000;POLYPROPYLENE GLYCOL, DIOL TYPE, 700;POLYPROPYLENE GLYCOL P 400;POLYPROPYLENE GLYCOL 700;POLYPROPYLENE GLYCOL 2000;POLYPROPYLENE GLYCOL 1000;POLYPROPYLENE GLYCOL 400 |
| CAS: | 25322-69-4 |
| MF: | CH4 |
| MW: | 16.04246 |
| EINECS: | 500-039-8 |
| Product Categories: | Polypropylene glycol;Alphabetic;P;POLB - POLYPolymer Standards;Water Soluble Polymers;Polymers;Ethers;Hydrophobic Polymers;Propylene Glycol;Hydrophobic Polymers;Materials Science;Polymer Science;Propylene Glycol |
| Mol File: | 25322-69-4.mol |
Polypropylene glycol Chemical Properties
| Melting point | -40 °C |
| Boiling point | >300 °C |
| density | 1.01 g/mL at 20 °C |
| Pour Point | -26 |
| Pour Point | -45 |
| vapor density | >1 (vs air) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| refractive index | n |
| Fp | 230 °C |
| storage temp. | Storage temp. 2-8°C |
| solubility | H2O: <0.01 % (w/w) at 25 °C |
| form | Viscous Liquid |
| Specific Gravity | 1.005 |
| color | White to light gray |
| Water Solubility | PRACTICALLY INSOLUBLE |
| FreezingPoint | -25 |
| FreezingPoint | -40 |
| Stability: | Stable. Substances to be avoided include strong oxidizing agents. |
| Cosmetics Ingredients Functions | SKIN CONDITIONING SOLVENT |
| InChI | 1S/C6H14O3/c1-5(8)4-9-6(2)3-7/h5-8H,3-4H2,1-2H3 |
| InChIKey | DUFKCOQISQKSAV-UHFFFAOYSA-N |
| SMILES | CC(O)CO |
| LogP | 0.01 at 25℃ |
| NIST Chemistry Reference | Polypropylene glycol 425(25322-69-4) |
| EPA Substance Registry System | Polypropylene glycol (25322-69-4) |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | TR5250000 |
| TSCA | TSCA listed |
| HS Code | 39072090 |
| Storage Class | 10 - Combustible liquids |
| Hazardous Substances Data | 25322-69-4(Hazardous Substances Data) |
| Chemical Properties | Polypropylene glycol is a transparent, colorless to light yellow viscous liquid. It is classified into three types based on its average molecular weight: 425, 1025, and 2025. It is non-volatile and non-corrosive. The lower molecular weight polymer is soluble in water, while the higher molecular weight variants are only slightly soluble in water but are soluble in oils, many hydrocarbons, aliphatic alcohols, ketones, esters, and similar solvents. The hydroxyl groups at both ends of the molecule can undergo esterification to form monoesters or diesters. The monoesters function as non-ionic surfactants. Polypropylene glycol can also react with alcohols to form ethers. Additionally, it serves as a solvent for vegetable oils, resins, and paraffin. |
| Uses | Hydraulic fluids, rubber lubricants, antifoamagents, intermediates in urethane foams, adhesives,coatings, elastomers, plasticizers, paint formula-tions, laboratory reagent. |
| Uses | Propylene glycol is used in the plastics industry for the manufacture of polyester fibers and alkyd resins. It is used as a main ingredient in automobile antifreeze and engine-cooling liquids and in brake and hydraulic fluids. It is used as a humectant in foods and cosmetics. It is used as a solvent for coloring or flavoring agents as well as in many oral, injectable or topical pharmaceuticals. |
| Preparation | Propylene oxide may be polymerized by methods similar to those described in the preceding section for ethylene oxide. Similarly, polymers of low molecular weight and of high molecular weight are of commercial interest. (a) Low molecular weight polymers Poly(propylene oxide)s of low molecular weight, i.e. in the range 500-3500, are important commercial materials principally on account of their extensive use in the production of both flexible and rigid polyurethane foams. At first, the most common polyether used in flexible polyurethane foams was a linear poly(propylene glycol) with a molecular weight of about 2000. This is prepared by polymerizing the oxide at about 160??C in the presence of propylene glycol and sodium hydroxide. The resulting polymer has the following general form: The majority of the hydroxyl groups in the polymer are secondary groups and are rather unreactive in the urethane reaction. Initially, this limitation was overcome by the preparation of pre-polymers and by the use of block copolymers with ethylene oxide. The latter products are 'tipped' with poly(ethylene oxide) and are terminated with primary hydroxyl groups of enhanced reactivity: (It may be noted that straight poly(ethylene glycol) is not satisfactory for foam production owing to its water sensitivity and tendency to crystallize.) The advent of more effective catalyst systems, however, now makes it possible for poly(propylene oxide)s to be used in the preparation of flexible polyurethane foams without recourse to the above mentioned procedures. Also, it is now common practice to use polyethers which are triols rather than diols; these lead to slightly cross-linked flexible foams with improved load bearing characteristics. The triols are produced by polymerizing propylene oxide in the presence of a trihydroxy compound such as glycerol, 1,1,1-trimethylolpropane or 1,2,6-hexane triol; the use of, for example, trimethylolpropane leads to the following polyether triol: Polyethers of molecular weights in the range 3000-3500 are normally used. For the production of rigid polyurethane foams, polyether triols of lower molecular weight (about 500) are used so that the degree of cross-linking is increased. Alternatively, polyethers of higher functionality may be used; these are prepared by polymerizing propylene oxide in the presence of hydroxy compounds such as pentaerythritol and sorbitol. (b) High molecular weight polymers Poly(propylene oxide)s of high molecular weight, i.e., greater than 100000 have been prepared by the use of initiators similar to those employed in the preparation of high molecular weight poly(ethylene oxide)s. The most extensively investigated initiators have been organoaluminium and organozinc compounds, generally with added co-initiators. As has been noted previously, the structural unit of poly(propylene oxide) contains an asymmetric carbon atom and the polymer can exhibit tacticity. Both atactic and isotactic poly(propylene oxide) have been prepared. As normally obtained, i.e. from D-L-propylene oxide, the isotactic polymer is optically inactive but optically active isotactic polymer has been produced from L-propylene oxide. Except for their optical activity, both forms of isotactic polymer are very similar in properties; they are both crystalline and have a melting point of 74??C. Isotactic poly(propylene oxide)s have not yet found commercial application. Atactic poly(propylene oxide) has been investigated as a rubber but does not appear to have been produced in any quantity. |
| Definition | ChEBI: Poly(propylene glycol) is a macromolecule composed of repeating propyleneoxy units. It is a hydroxypolyether and a poly(ether) macromolecule. |
| General Description | Colorless liquid that is odorless or has a mild sweet odor. May float or sink in water. |
| Reactivity Profile | Poly(propylene glycol) is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. |
| Health Hazard | The compound has a very low toxicity; few, if any, symptoms will be observed. Contact of liquid with eyes causes slight transient pain and irritation similar to that caused by a mild soap. |
| Flammability and Explosibility | Non flammable |
| Safety Profile | Poison byintraperitoneal and intravenous routes.When heated to decomposition it emitsacrid smoke and irritating fumes. |
| Solubility in organics | Acetone, benzene, chloroform, dioxane, THF, toluene, water |
| Toxics Screening Level | The initial threshold screening level (ITSL) for polypropylene glycol (MW 999), is 49 μg/m3 based on an annual averaging time. |
Polypropylene glycol Preparation Products And Raw materials
| Raw materials | Propylene oxide-->Propylene glycol |
| Preparation Products | antistatic agent F695 |
