CAS 39544-74-6|benzotript

Introduction：Basic information about CAS 39544-74-6|benzotript, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. benzotript BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	benzotript
CAS Number	39544-74-6	Molecular Weight	342.78
Density	/	Boiling Point	643.7ºC at 760 mmHg
Molecular Formula	C₁₈H₁₅ClN₂O₃	Melting Point	/
MSDS	/	Flash Point	343.1ºC

Names

Name	benzotript
Synonym	More Synonyms

benzotript BiologicalActivity

Description	Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>GPCR/G Protein >>Cholecystokinin ReceptorResearch Areas >>Inflammation/Immunology
References	[1]. N M Hoosein, et al. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res. 1988 Dec 15;48(24 Pt 1):7179-83. [2]. C Niederau, et al. Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin. Gastroenterology. 1985 May;88(5 Pt 1):1192-204.

Description

Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines[1].

Related Catalog

Research Areas >>CancerSignaling Pathways >>GPCR/G Protein >>Cholecystokinin ReceptorResearch Areas >>Inflammation/Immunology

References

[1]. N M Hoosein, et al. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res. 1988 Dec 15;48(24 Pt 1):7179-83.

[2]. C Niederau, et al. Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin. Gastroenterology. 1985 May;88(5 Pt 1):1192-204.

Chemical & Physical Properties

Boiling Point	643.7ºC at 760 mmHg
Molecular Formula	C₁₈H₁₅ClN₂O₃
Molecular Weight	342.78
Flash Point	343.1ºC
Exact Mass	342.07700
PSA	82.19000
LogP	3.63790
InChIKey	QJERBBQXOMUURJ-INIZCTEOSA-N
SMILES	O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1

Safety Information

HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

N-carbamothioyl-4-chloro-benzamide

EINECS 254-500-0

N-p-Chlorbenzoyl-thioharnstoff

(4-chloro-benzoyl)-thiourea

N-p-chlorobenzoyl-L-tryptophane

N-(4-chlorobenzoyl)-L-tryptophan

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