CAS 39537-23-0|L-Alanyl-L-Glutamine
| Common Name | L-Alanyl-L-Glutamine | ||
|---|---|---|---|
| CAS Number | 39537-23-0 | Molecular Weight | 217.22 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 615℃ |
| Molecular Formula | C8H15N3O4 | Melting Point | 215 °C |
| MSDS | ChineseUSA | Flash Point | >110° |
Names
| Name | (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid |
|---|---|
| Synonym | More Synonyms |
L-Alanyl-L-Glutamine BiologicalActivity
| Description | L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations[1]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease |
| Target | Human Endogenous Metabolite |
| In Vitro | L-Alanyl-L-glutamine (2 mM; 24 hours) partially or fully attenuates chronic insulin secretion, and IR-β and COX IV levels which are decreased when β-cells were exposed to macrophages following stimulation in vitro (IMMs)[1]. L-Alanyl-L-glutamine -dependent β-cell protection mediated by coordinated effects on the glutamine-GSH axis, and the HSP pathway, maintenance of mitochondrial metabolism and stimulus-secretion coupling essential for insulin release[1]. |
| References | [1]. Cruzat VF,et al. Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge. J Endocrinol. 2015 Mar;224(3):261-71. |
Chemical & Physical Properties
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 615℃ |
| Melting Point | 215 °C |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.22 |
| Flash Point | >110° |
| Exact Mass | 146.069138 |
| PSA | 106.41000 |
| LogP | -1.28 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.564 |
| InChIKey | HJCMDXDYPOUFDY-WHFBIAKZSA-N |
| SMILES | CC(N)C(=O)NC(CCC(N)=O)C(=O)O |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S23-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| HS Code | 2924199090 |
Customs
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| UNII-U5JDO2770Z |
| (2S)-2-((2S)-2-Aminopropanoylamino)-4-carbamoylbutanoic acid |
| ZY1&VMYVQ2VZ &&L-L Form |
| glutaminic acid |
| Gln |
| L-Ala-L-Gln |
| EINECS 475-290-9 |
| glutamine |
| L-Gln |
| Pentanoic acid, 2,5-diamino-5-oxo-, (S)- |
| L-Alanyl-L-glutamine |
| Levoglutamide |
| (S)-5-Amino-2-[(S)-2-aminopropanamido]-5-oxopentanoic acid |
| L-Glutamine,L-alanyl |
| 2,5-Diamino-5-oxopentanoic acid, (S)- |
| (2S)-2-amino-4-carbamoylbutanoic acid |
| Alanyl-glutamine,Glutamine-S |
| Ala-Gln |
| 2-Aminoglutaramic acid, L- |
| (S)-(+)-Glutamine |
| 5-Hydroxy-5-imino-L-norvaline |
| N(2)-L-alanyl-L-glutamine |
| Glutamine-S |
| Alanyl-glutamine |
| L-Norvaline, 5-hydroxy-5-imino- |
| L-Glutamic Acid g-Amide |
| L-Glutamic acid γ-amide |
| N-L-alanyl-L-glutamine |
| L-Glutamine, N2-L-alanyl- |
| L-Glutamine |
| l-alanyl-l-glutamin |
| l-(+)-glutamic acid-5-amide |
| L-Glutamic acid 5-amide |
| H-Ala-Gln-OH |
| GLUTAMINE, L- |
| (2S)-5-Amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid |
| L-Glutamine, L-alanyl- |
| MFCD00133046 |
| S(+)-Glutamic acid 5-amide |
| Alanyl glutamine |
