Introduction：Basic information about CAS 13292-45-0|Rifamycin,3-[(1-piperazinylimino)methyl]-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rifamycin,3-[(1-piperazinylimino)methyl]- |
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| CAS Number | 13292-45-0 | Molecular Weight | 808.91400 |
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| Density | 1.35g/cm3 | Boiling Point | / |
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| Molecular Formula | C42H56N4O12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-Demethyl Rifampin |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.35g/cm3 |
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| Molecular Formula | C42H56N4O12 |
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| Molecular Weight | 808.91400 |
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| Exact Mass | 808.38900 |
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| PSA | 228.94000 |
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| LogP | 4.39790 |
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| Index of Refraction | 1.631 |
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| InChIKey | FKKVFHDDYXJFFL-MOSFFKILSA-N |
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| SMILES | COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(c(C=NN5CCNCC5)c(O)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- KD1923000
- CHEMICAL NAME :
- 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl -8-(N-1-piperazinylfo rmimidoyl)-, 21- acetate
- CAS REGISTRY NUMBER :
- 13292-45-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C42-H56-N4-O12
- MOLECULAR WEIGHT :
- 809.02
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 695 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 100 mg/L
- REFERENCE :
- BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 60,96,1974
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Synonyms
| 4-N-Demethylrifampicin |
| rifaldehyde piperazin-1-ylhydrazone |
| Rifampicin AF/AP |
| 3-(piperazin-1-ylimino-methyl)-rifamycin |
| N-Demethylrifampin |
| AF/AP |
| N-Demethylrifampicin |
| Rifampicin AF/A |
| 3-(piperidinyliminomethyl)rifamycin SV |
| Demethylrifampicin |
