CAS 138154-39-9|C-1311
| Common Name | C-1311 | ||
|---|---|---|---|
| CAS Number | 138154-39-9 | Molecular Weight | 350.41400 |
| Density | 1.32g/cm3 | Boiling Point | 605.8ºC at 760mmHg |
| Molecular Formula | C20H22N4O2 | Melting Point | / |
| MSDS | USA | Flash Point | 320.2ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5-((2-(diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.32g/cm3 |
|---|---|
| Boiling Point | 605.8ºC at 760mmHg |
| Molecular Formula | C20H22N4O2 |
| Molecular Weight | 350.41400 |
| Flash Point | 320.2ºC |
| Exact Mass | 350.17400 |
| PSA | 69.87000 |
| LogP | 2.97100 |
| Vapour Pressure | 2.86E-15mmHg at 25°C |
| Index of Refraction | 1.68 |
| InChIKey | CUNDRHORZHFPLY-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCNc1ccc2ncn3c4ccc(O)cc4c(=O)c1c23 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| RIDADR | NONH for all modes of transport |
Articles23
More Articles| DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells. J. Pharmacol. Exp. Ther. 346(3) , 393-405, (2013) Imidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the uni... | |
| Metabolic transformation of antitumor acridinone C-1305 but not C-1311 via selective cellular expression of UGT1A10 increases cytotoxic response: implications for clinical use. Drug Metab. Dispos. 41(2) , 414-21, (2013) The acridinone derivates 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) are promising antitumor agents with high activ... | |
| Development and validation of an LC-UV method for the quantification and purity determination of the novel anticancer agent C1311 and its pharmaceutical dosage form. J. Pharm. Biomed. Anal. 39(1-2) , 46-53, (2005) C1311 (5-[[2-(diethylamino)ethyl]amino]-8-hydroxyimidazo [4,5,1-de]-acridin-6-one-dihydrochloride trihydrate) is the lead compound from the group of imidazoacridinones, a novel group of rationally des... |
Synonyms
| 5-[[(diethylamino)ethyl]amino]-8-hydroxyimidazo[4,5,1-de]-acridine-6-one |
| C 1311 |
| XLS-002 |
| 6H-Imidazo(4,5,1-de)acridin-6-one,5-((2-(diethylamino)ethyl)amino)-8-hydroxy |
| 5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo(4,5,1-de)acridin-6-one |
