Introduction：Basic information about CAS 61438-64-0|Closantel Sodium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Closantel Sodium |
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| CAS Number | 61438-64-0 | Molecular Weight | 685.06 |
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| Density | / | Boiling Point | 590.5ºC at 760 mmHg |
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| Molecular Formula | C22H13Cl2I2N2NaO2 | Melting Point | >230ºC (dec.) |
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| MSDS | / | Flash Point | 310.9ºC |
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Names
| Name | Closantel sodium |
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| Synonym | More Synonyms |
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Closantel Sodium BiologicalActivity
| Description | Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
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| References | [1]. Bacon JA, et al. Comparative in vitro effects of closantel and selected beta-ketoamide anthelmintics on a gastrointestinal nematode and vertebrate liver cells. J Vet Pharmacol Ther. 1998 Jun;21(3):190-8. [2]. Macielag MJ, et al. Substituted salicylanilides as inhibitors of two-component regulatory systems in bacteria. J Med Chem. 1998 Jul 30;41(16):2939-45. [3]. Waruiru RM. Efficacy of closantel, albendazole and levamisole on an ivermectin resistant strain of Haemonchus contortus in sheep. Vet Parasitol. 1997 Dec 15;73(1-2):65-71. |
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Chemical & Physical Properties
| Boiling Point | 590.5ºC at 760 mmHg |
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| Melting Point | >230ºC (dec.) |
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| Molecular Formula | C22H13Cl2I2N2NaO2 |
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| Molecular Weight | 685.06 |
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| Flash Point | 310.9ºC |
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| PSA | 113.25000 |
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| LogP | 4.51228 |
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| InChIKey | OSRFZYBZFCOAGP-UHFFFAOYSA-N |
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| SMILES | Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O.[Na] |
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| Storage condition | Refrigerator |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2926909090 |
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Customs
| HS Code | 2926909090 |
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| Summary | HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| EINECS 262-794-7 |
| MFCD03427328 |
| Sodium 2-({5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}carbamoyl)-1-hydroxy-4,6-diiodo-2,4-cyclohexadiene-1-carboxylate |
| 2,4-Cyclohexadiene-1-carboxylic acid, 2-[[[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]amino]carbonyl]-1-hydroxy-4,6-diiodo-, sodium salt (1:1) |
| Closantel (sodium) |
