Introduction：Basic information about CAS 311795-38-7|Glutaminase C-IN-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Glutaminase C-IN-1 |
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| CAS Number | 311795-38-7 | Molecular Weight | 475.42000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H27BrN2O | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one |
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| Synonym | More Synonyms |
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Glutaminase C-IN-1 BiologicalActivity
| Description | Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Cancer |
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| References | [1]. Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):394-9. |
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Chemical & Physical Properties
| Molecular Formula | C27H27BrN2O |
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| Molecular Weight | 475.42000 |
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| Exact Mass | 474.13100 |
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| PSA | 32.34000 |
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| LogP | 7.11580 |
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| InChIKey | NVFRRJQWRZFDLM-UHFFFAOYSA-N |
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| SMILES | CN(C)c1ccc(C2Nc3ccc4ccccc4c3C3=C2C(=O)CC(C)(C)C3)cc1Br |
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| Storage condition | 2-8℃ |
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Safety Information
| Hazard Statements | H413 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| QC-219 |
| 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one |
| Glutaminase C-IN-1 |
