Introduction：Basic information about CAS 1335210-23-5|Dolutegravir intermediate-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dolutegravir intermediate-1 |
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| CAS Number | 1335210-23-5 | Molecular Weight | 315.276 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 474.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C13H17NO8 | Melting Point | / |
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| MSDS | / | Flash Point | 240.5±28.7 °C |
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Names
| Name | 2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester |
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| Synonym | More Synonyms |
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Dolutegravir intermediate-1 BiologicalActivity
| Description | Dolutegravir intermediate-1 is a novel synthetic intermediate of dolutegravir extracted from patent WO 2016125192 A2. Dolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Others |
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| References | [1]. Sivaram Prasad, et al. Process for the preparation of dolutegravir . WO 2016125192 A2. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 474.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C13H17NO8 |
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| Molecular Weight | 315.276 |
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| Flash Point | 240.5±28.7 °C |
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| Exact Mass | 315.095428 |
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| PSA | 113.29000 |
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| LogP | -1.00 |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.536 |
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| InChIKey | XAXGEECGULRZGN-UHFFFAOYSA-N |
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| SMILES | COC(=O)c1c(OC)c(=O)c(C(=O)O)cn1CC(OC)OC |
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| Storage condition | 2-8℃ |
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Synonyms
| 1-(2,2-Dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid |
| 2,5-Pyridinedicarboxylic acid, 1-(2,2-dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-, 2-methyl ester |
| 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid |
| Dolutegravir intermediate-1 |
| 1-(2,2-Dimethoxyethyl)-1,4-dihydro-3-methoxy-4-oxo-2,5-pyridinedicarboxylic acid 2-methyl ester |
