CAS 13027-33-3|3β,5α-Dihydroxycholestan-6-one

Introduction：Basic information about CAS 13027-33-3|3β,5α-Dihydroxycholestan-6-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 3β,5α-Dihydroxycholestan-6-one BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	3β,5α-Dihydroxycholestan-6-one
CAS Number	13027-33-3	Molecular Weight	418.652
Density	1.1±0.1 g/cm3	Boiling Point	528.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₇H₄₆O₃	Melting Point	/
MSDS	/	Flash Point	287.7±25.2 °C

Names

Name	5alpha-cholestan-3beta,5alpha-diol-6-one
Synonym	More Synonyms

3β,5α-Dihydroxycholestan-6-one BiologicalActivity

Description	5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM[1].
Related Catalog	Research Areas >>Cardiovascular Disease
In Vitro	5α-Hydroxy-6-keto cholesterol (0.01, 0.1, 1, 10 μM) is cytotoxic to cultured 16-HBE cells[1].
References	[1]. Melissa K Pulfer, et al. Formation of biologically active oxysterols during ozonolysis of cholesterol present in lung surfactant. J Biol Chem. 2004 Jun 18;279(25):26331-8.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	528.9±45.0 °C at 760 mmHg
Molecular Formula	C₂₇H₄₆O₃
Molecular Weight	418.652
Flash Point	287.7±25.2 °C
Exact Mass	418.344696
PSA	57.53000
LogP	7.00
Vapour Pressure	0.0±3.2 mmHg at 25°C
Index of Refraction	1.531
InChIKey	SJZZRXMQSAXCFD-ZCBMJONGSA-N
SMILES	CC(C)CCCC(C)C1CCC2C3CC(=O)C4(O)CC(O)CCC4(C)C3CCC12C

Synonyms

CHOLESTANE-6-OXO-3,5-DIOL

Cholestan-6-one, 3,5-dihydroxy-, (3β,5α)-

(3β,5α)-3,5-Dihydroxycholestan-6-one

CHOLESTANE-6-OXO-3BETA,5ALPHA-DIOL

5ALPHA-HYDROXY-6-KETO CHOLESTEROL

YS-64

yakkasterone

3β,5α-Dihydroxycholestan-6-one

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