CAS 78-79-5|isoprene
Introduction：Basic information about CAS 78-79-5|isoprene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | isoprene | ||
|---|---|---|---|
| CAS Number | 78-79-5 | Molecular Weight | 68.117 |
| Density | 0.68 | Boiling Point | 34 ºC |
| Molecular Formula | C5H8 | Melting Point | -146 ºC |
| MSDS | ChineseUSA | Flash Point | -48 ºC |
| Symbol | GHS02, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | isoprene |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 0.68 |
|---|---|
| Boiling Point | 34 ºC |
| Melting Point | -146 ºC |
| Molecular Formula | C5H8 |
| Molecular Weight | 68.117 |
| Flash Point | -48 ºC |
| Exact Mass | 68.062599 |
| LogP | 2.41 |
| Vapour density | 2.35 (vs air) |
| Vapour Pressure | 549.0±0.0 mmHg at 25°C |
| Index of Refraction | 1.400 |
| InChIKey | RRHGJUQNOFWUDK-UHFFFAOYSA-N |
| SMILES | C=CC(=C)C |
| Water Solubility | 0.07 g/100 mL |
| Freezing Point | -145.96℃ |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 gm/m3/4H
- TOXIC EFFECTS :
- Behavioral - general anesthetic Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 139 gm/m3/2H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 157 mg/kg/9W-C
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3400 mg/m3/22W-I
- TOXIC EFFECTS :
- Brain and Coverings - changes in brain weight Lungs, Thorax, or Respiration - changes in lung weight Kidney, Ureter, Bladder - changes in kidney weight
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3400 mg/m3/17W-I
- TOXIC EFFECTS :
- Behavioral - changes in psychophysiological tests
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 3400 mg/m3/17W-I
- TOXIC EFFECTS :
- Behavioral - alteration of classical conditioning Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 438 ppm/6H/12D (Continuous)
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,141,1988 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-POLAND:TWA 100 mg/m3 JAN 1993 OEL-RUSSIA:STEL 40 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 40940 No. of Facilities: 2278 (estimated) No. of Industries: 36 No. of Occupations: 43 No. of Employees: 58102 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 40940 No. of Facilities: 123 (estimated) No. of Industries: 6 No. of Occupations: 15 No. of Employees: 3703 (estimated) No. of Female Employees: 578 (estimated)
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 438 ppm/6H/12D (Continuous)
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,141,1988 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,215,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-POLAND:TWA 100 mg/m3 JAN 1993 OEL-RUSSIA:STEL 40 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 40940 No. of Facilities: 2278 (estimated) No. of Industries: 36 No. of Occupations: 43 No. of Employees: 58102 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 40940 No. of Facilities: 123 (estimated) No. of Industries: 6 No. of Occupations: 15 No. of Employees: 3703 (estimated) No. of Female Employees: 578 (estimated)
Safety Information
| Symbol | GHS02, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H224-H341-H350-H411 |
| Precautionary Statements | P201-P210-P280-P308 + P313-P370 + P378-P403 + P235 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US) |
| Hazard Codes | F+:Highlyflammable;T:Toxic; |
| Risk Phrases | R12;R45;R52/53;R68 |
| Safety Phrases | S53-S45-S61 |
| RIDADR | UN 1218 3/PG 1 |
| WGK Germany | 1 |
| RTECS | NT4037000 |
| Packaging Group | I |
| Hazard Class | 3 |
| HS Code | 4002601000 |
Customs
| HS Code | 4002601000 |
|---|
Articles61
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Synonyms
| 2-methyl-buta-1,3-diene |
| BUFFER PH7.20 |
| EINECS 201-143-3 |
| BUFFER ACETATE |
| 2-methyl-1,3-butadiene |
| 3-methyl-1,2-butadiene |
| Isopentadiene |
| Vita-crop |
| 2-methylethene |
| decyclo-C5 |
| MFCD00137248 |
| Isoprene |
